216578-30-2

Basic information

• Product Name: Benzenesulfonamide, N-3-cyclopenten-1-yl-4-methyl- (9CI)
• Synonyms: Benzenesulfonamide, N-3-cyclopenten-1-yl-4-methyl- (9CI);N-3-Cyclopenten-1-yl-4-methylbenzenesulfonamide
• CAS NO: 216578-30-2
• Molecular Formula: C₁₂H₁₅NO₂S
• Molecular Weight: 237.318
• Product Categories: SULFONAMIDE
• Mol File: 216578-30-2.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzenesulfonamide, N-3-cyclopenten-1-yl-4-methyl- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonamide, N-3-cyclopenten-1-yl-4-methyl- (9CI)(216578-30-2)
• EPA Substance Registry System: Benzenesulfonamide, N-3-cyclopenten-1-yl-4-methyl- (9CI)(216578-30-2)

Safety Data

• Hazardous Substances Data: 216578-30-2(Hazardous Substances Data)

Usage

Description

Benzenesulfonamide, N-3-cyclopenten-1-yl-4-methyl(9CI) is a chemical compound with the molecular formula C12H15NO2S. It is a sulfonamide derivative featuring a cyclopenten-1-yl and methyl substituents, which contribute to its diverse biological activities. Benzenesulfonamide, N-3-cyclopenten-1-yl-4-methyl(9CI) holds promise in pharmaceuticals and agrochemicals due to its potential applications as a carbonic anhydrase inhibitor, anti-glaucoma agent, antifungal, and antibacterial agent.

Uses

Used in Pharmaceutical Industry:
Benzenesulfonamide, N-3-cyclopenten-1-yl-4-methyl(9CI) is used as a carbonic anhydrase inhibitor for its potential role in treating conditions such as glaucoma. It helps in reducing intraocular pressure by inhibiting the enzyme carbonic anhydrase, which is involved in the production of aqueous humor in the eye.
Used in Antifungal Applications:
In the pharmaceutical and agrochemical industries, Benzenesulfonamide, N-3-cyclopenten-1-yl-4-methyl(9CI) is utilized as an antifungal agent. It exhibits properties that can inhibit the growth of certain fungi, making it a candidate for the development of antifungal drugs or treatments.
Used in Antibacterial Applications:
Benzenesulfonamide, N-3-cyclopenten-1-yl-4-methyl(9CI) also serves as an antibacterial agent, effective against the growth of specific bacteria. Its potential use in this area could contribute to the development of new antibiotics or complement existing treatments in the medical field.
Further research and development may uncover additional applications and benefits of Benzenesulfonamide, N-3-cyclopenten-1-yl-4-methyl(9CI) in various industries, expanding its utility and impact on human health and agriculture.

Upstream product

• 91469-55-5 cyclopent-3-en-1-amine hydrogen chloride 
• 172791-01-4 6-(toluene-4-sulfonyl)-6-aza-bicyclo[3.1.0]hex-2-ene 
• 55962-05-5 [N-(p-tolylsulfonyl)imino]phenyliodinane 
• 542-92-7 cyclopenta-1,3-diene 
• 14320-38-8 cyclopent-3-enol 
• 253680-54-5 methanesulfonic acid cyclopent-3-enyl ester 

Relevant articles and documents

Synthesis and reactions of cyclopentadiene monoaziridine: A concise approach to the core of agelastatin A

An improved protocol for the preparation of cyclopentadiene monoaziridine is described (88% yield). The utility of cyclopentadiene monoaziridine is demonstrated by its use in (i) the shortest synthetic entry into 4-amino substituted cyclopentenes and (ii)

Synthesis and enantioselective rearrangement of 4-amino-substituted cyclopentene oxides

Several N-mono- and diprotected alkenes have been prepared and the stereoselectivity of their epoxidation has been investigated: N-monoprotected alkenes give cis epoxides preferentially (due to hydrogen bonding directed epoxidations) whereas N-diprotected alkenes produce trans epoxides exclusively (due to steric effects). Chiral lithium amide base-mediated rearrangement of a cis-monoprotected epoxide generated the corresponding amino-cyclopentenol in good yield and with an enantiomeric excess of 60%.