216578-85-7Relevant articles and documents
Synthesis of α-heterosubstituted glycine derivatives from dihaloethanamides
Bailey, Patrick D.,Baker, S. Richard,Boa, Andrew N.,Clayson, Joanne,Rosair, Georgina M.
, p. 7755 - 7758 (1998)
A range of protected α-heterosubstituted analogues of glycine were synthesised from starting materials of the type CHFX-CONHR [X = Cl, Br, I; R = CH2Ph, (s)-CHMePh]; the final products included derivatives of glycine possessing N, O, F or S in the α-position, and the first example of a free α-fluoro-α-amino acid (α-fluorobetaine) whose structure was confirmed by X-ray crystal structure determination.