21681-63-0

Basic information

• Product Name: 2(3H)-Furanone, 3-cyclohexylidenedihydro-
• Synonyms: 3-Cyclohexyliden-dihydro-furan-2-on;2-Cyclohexyliden-4-hydroxy-buttersaeure-lacton;3-cyclohexylidene-dihydro-furan-2-one;2-cyclohexylidene-4-hydroxy-butyric acid-lactone
• CAS NO: 21681-63-0
• Molecular Formula: C10H14O2
• Molecular Weight: 166.22
• Mol File: 21681-63-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2(3H)-Furanone, 3-cyclohexylidenedihydro-(CAS DataBase Reference)
• NIST Chemistry Reference: 2(3H)-Furanone, 3-cyclohexylidenedihydro-(21681-63-0)
• EPA Substance Registry System: 2(3H)-Furanone, 3-cyclohexylidenedihydro-(21681-63-0)

Safety Data

• Hazardous Substances Data: 21681-63-0(Hazardous Substances Data)

Usage

Structure

Cyclic, unsaturated ketone with a furanone ring and a cyclohexylidene side chain

Usage

Flavoring agent and fragrance ingredient in food, beverages, and personal care items

Odor

Sweet, caramel-like

Function

Enhances taste and aroma of food products

Biological activities

Potential antimicrobial and anti-inflammatory properties

Applications

Pharmaceutical and cosmetic industries

Upstream product

• 96-48-0 4-butanolide 
• 108-94-1 cyclohexanone 
• 66909-41-9 O-ethyl S-(tetrahydro-2-oxo-3-furanyl) thiocarbonate 
• 77772-24-8 α-(diphenylmethylsilyl)-γ-butyrolactone 

Downstream Products

• 32591-07-4 α-(cyclohex-1-enyl)-γ-butyrolactone 
• 92015-94-6 4-Hydroxy-2-cyclohexyliden-buttersaeure 

Relevant articles and documents

New Methods for Stereoselective Synthesis of α-Alkylidene-γ-butyrolactones Using Monoanion of O-Ethyl S-(Tetrahydro-2-oxo-3-furanyl) Thiocarbonate and Dianion of α-Mercapto-γ-butyrolactone

The lithium enolates of O-ethyl S-(tetrahydro-2-oxo-3-furanyl) dithiocarbonate and thiocarbonate were found to be efficient reagents for the stereoselective synthesis of α-alkylidene-γ-butyrolactones from carbonyl compounds.The dianion of α-mercapto-γ-butyrolactone was successfully generated by treatment of α-mercapto-γ-butyrolactone with 2.2 equivalents of lithium diisopropylamide in the presence of N,N,N',N'-tetramethylethylenediamine at -78 deg C in THF.The dianion thus formed has been utilized for the efficient and stereoselective synthesis of α-alkylidene-γ-butyrolactones from carbonyl compounds.