216854-54-5

Basic information

• Product Name: N-(2,3-DIBROMOPROPYL)-N'-FORMYLFORMIC HYDRAZIDE
• Synonyms: N-(2,3-DIBROMOPROPYL)-N'-FORMYLFORMIC HYDRAZIDE
• CAS NO: 216854-54-5
• Molecular Formula: C5H8Br2N2O2
• Molecular Weight: 287.94
• Mol File: 216854-54-5.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(2,3-DIBROMOPROPYL)-N'-FORMYLFORMIC HYDRAZIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2,3-DIBROMOPROPYL)-N'-FORMYLFORMIC HYDRAZIDE(216854-54-5)
• EPA Substance Registry System: N-(2,3-DIBROMOPROPYL)-N'-FORMYLFORMIC HYDRAZIDE(216854-54-5)

Safety Data

• Hazardous Substances Data: 216854-54-5(Hazardous Substances Data)

Upstream product

• 216854-53-4 1-allyl-1,2-diformylhydrazine 

Downstream Products

• 162887-23-2 4-bromo-1,2-diformylpyrazolidine 
• 216854-55-6 4-(acetylthio)-1,2-diformylpyrazolidine 

Relevant articles and documents

New straightforward synthesis and characterization of a unique 1β- methylcarbapenem antibiotic biapenem bearing a σ-symmetric bicyclotriazoliumthio group as the pendant moiety

Biapenem 1, (1R,5S,6S,)-2-[(6,7-dihydro-5H-pyrazolo[1,2- α][1,2,4]triazolium-6-yl)thio]-6-yl)thio]-6-[(R)-1-hydroxyethyl]-1- methylcarbapen-2-em-3-carboxylate, is a new non-natural 1β-methylcarbapenem antibiotic which exhibits a wide range of antibacterial activity, remarkable chemical stability, and extensive stability against human renal dehydropeptidase-I. Mercaptobicyclotriazolium chloride 2 useful for the pendant moiety of 1 was successfully synthesized starting from hydrazine hydrate 3 along an economically available synthetic route. The thiol 2 was efficiently exploited for an expeditious synthesis of biapenem 1. Characterization (crystal structure, nonbonded S- - -O interaction, conformational analysis, and CH- - -O hydrogen bonds) of 1 was investigated by its X-ray crystallographic, 1H NMR, and deuteration experiment analyses.