216868-57-4 Usage
Description
(S)-N-((3-(3-fluoro-4-Morpholinophenyl)-2-oxooxazolidin-5-yl)Methyl)ethanethioaMide, also known as Deacetyl Linezolid Thioacetamide, is an impurity of Linezolid (L466500), an oxazolidinone antimicrobial agent. It is characterized by its off-white to pale yellow solid appearance. (S)-N-((3-(3-fluoro-4-Morpholinophenyl)-2-oxooxazolidin-5-yl)Methyl)ethanethioaMide inhibits bacterial mRNA translation, playing a crucial role in the development and efficacy of Linezolid as an antimicrobial drug.
Uses
Used in Pharmaceutical Industry:
(S)-N-((3-(3-fluoro-4-Morpholinophenyl)-2-oxooxazolidin-5-yl)Methyl)ethanethioaMide is used as an impurity in the development and production of Linezolid (L466500), an oxazolidinone antimicrobial agent. Its presence is essential for understanding the purity and quality of Linezolid, ensuring the drug's effectiveness in inhibiting bacterial mRNA translation and combating infections.
Used in Quality Control and Analysis:
In the pharmaceutical industry, (S)-N-((3-(3-fluoro-4-Morpholinophenyl)-2-oxooxazolidin-5-yl)Methyl)ethanethioaMide serves as a reference compound for quality control and analysis. It helps in monitoring the purity and consistency of Linezolid, ensuring that the final product meets the required standards and is safe for use in treating bacterial infections.
Used in Research and Development:
(S)-N-((3-(3-fluoro-4-Morpholinophenyl)-2-oxooxazolidin-5-yl)Methyl)ethanethioaMide is also used in research and development for the study of oxazolidinone antimicrobial agents. It aids in understanding the structure-activity relationship and the mechanism of action of Linezolid, contributing to the discovery of new and improved antimicrobial drugs.
Check Digit Verification of cas no
The CAS Registry Mumber 216868-57-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,6,8,6 and 8 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 216868-57:
(8*2)+(7*1)+(6*6)+(5*8)+(4*6)+(3*8)+(2*5)+(1*7)=164
164 % 10 = 4
So 216868-57-4 is a valid CAS Registry Number.
216868-57-4Relevant articles and documents
Oxazolidinone antibacterial agents having a thiocarbonyl functionality
-
Page column 30-31, (2010/01/30)
The present invention provides compounds of Formula 1: or pharmaceutical acceptable salts thereof wherein A, G and R1are as defined in the claims which are antibacterial agents.
Oxazolidinone antibacterial agents having a thiocarbonyl functionality
-
, (2008/06/13)
The present invention provides compounds of Formula 1 or pharmaceutical acceptable salts thereof wherein A, G and R, are as defined in the claims which are antibacterial agents.
