2169-23-5Relevant articles and documents
Design of a Functional Chromene-Type Kobayashi Precursor: Gram-Scale Total Synthesis of Natural Xanthones by Highly Regioselective Aryne Annulation
Xu, Yuan-Ze,Sha, Feng,Wu, Xin-Yan
supporting information, p. 1066 - 1071 (2020/12/18)
The 2,2-dimethyl-2H-chromene motif is widely found in many bioactive molecules, and is a privileged structure in the pharmaceutical arena. We have developed a concise and regioselective approach to chromenes and chromanes through an aryne-based synthetic
Facile synthesis of salmochelin S1, S2, MGE, DGE, and TGE
Yu, Xiaolong,Dai, Yijing,Yang, Tao,Gagné, Michel R.,Gong, Hegui
, p. 144 - 151 (2011/03/17)
Salmochelin S1, S2, MGE, DGE, and TGE were prepared through amide bond connection of an aryl C-glucosyl acyl chloride (Ar1COCl) and serine ester amines, followed by hydrogenolysis of the per-benzylated precursors. Each synthesis employed a highly diastereoselective Ni-catalyzed Negishi approach to the aryl C-glycoside subunit.
