21690-63-1

Basic information

• Product Name: 2,2-bis(4-methoxyphenyl)tetrahydrofuran
• Synonyms: 2,2-bis(4-methoxyphenyl)tetrahydrofuran
• CAS NO: 21690-63-1
• Molecular Weight: 284.355
• Mol File: 21690-63-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,2-bis(4-methoxyphenyl)tetrahydrofuran(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-bis(4-methoxyphenyl)tetrahydrofuran(21690-63-1)
• EPA Substance Registry System: 2,2-bis(4-methoxyphenyl)tetrahydrofuran(21690-63-1)

Safety Data

• Hazardous Substances Data: 21690-63-1(Hazardous Substances Data)

Upstream product

• 699-19-4 4-methoxyphenylmagnesium chloride 
• 40877-19-8 4-chloro-1-(4-methoxyphenyl)butan-1-one 
• 96-48-0 4-butanolide 
• 13139-86-1 4-methoxyphenyl magnesium bromide 

Downstream Products

• 1618101-85-1 2-(4-methoxy-2-methylphenyl)-2-(4-methoxyphenyl)tetrahydrofuran 
• 1618101-87-3 5-methoxy-2-(2-(4-methoxyphenyl)tetrahydrofuran-2-yl)benzaldehyde 
• 1618101-86-2 2-(2-chloro-4-methoxyphenyl)-2-(4-methoxyphenyl)tetrahydrofuran 

Relevant articles and documents

Regioselective desymmetrization of diaryltetrahydrofurans via directed ortho-lithiation: An unexpected help from green chemistry

An efficient functionalization of diaryltetrahydrofurans via a regioselective THF-directed ortho-lithiation is first described. This reaction can be successfully carried out in cyclopentyl methyl ether as a greener alternative to Et2O, with better results in terms of yield and selectivity and, surprisingly, also in protic eutectic mixtures competitively with protonolysis.