21694-91-7Relevant articles and documents
Structure-Activity Relationship of novel phenylacetic CXCR1 inhibitors
Sablone, Manolo Rocco,Cesta, Maria Candida,Moriconi, Alessio,Aramini, Andrea,Bizzarri, Cinzia,Giacinto, Claudia Di,Bitondo, Rosa Di,Gloaguen, Isabelle,Aschi, Massimiliano,Crucianelli, Marcello,Bertini, Riccardo,Allegretti, Marcello
supporting information; experimental part, p. 4026 - 4030 (2010/04/02)
We reported recently the Structure-Activity Relationship (SAR) of a class of CXCL8 allosteric modulators. They invariably share a 2-arylpropionic moiety so far considered a key structural determinant of the biological activity. We show the results of rece