217192-22-8

Basic information

• Product Name: (4-PYRID-4-YLPHENYL)METHANOL
• Synonyms: 4-(4-HYDROXYMETHYLPHENYL)PYRIDINE;(4-PYRIDIN-4-YL-PHENYL)-METHANOL;(4-PYRID-4-YLPHENYL)METHANOL;4-[4-(Hydroxymethyl)phenyl]pyridine 97%;3-(2-Carboxypyridin-4-yl)benzyl alcohol;3-(2-Fluoropyridin-4-yl)benzyl alcohol;3-(2-Methylpyridin-4-yl)benzyl alcohol;3-(3-Carboxypyridin-4-yl)benzyl alcohol
• CAS NO: 217192-22-8
• Molecular Formula: C₁₂H₁₁NO
• Molecular Weight: 185.22
• Mol File: 217192-22-8.mol
• Article Data: 6

Chemical Properties

• Melting Point: 173 °C
• Boiling Point: 350.2 °C at 760 mmHg
• Flash Point: 165.6 °C
• Appearance: /
• Density: 1.145 g/cm³
• Vapor Pressure: 1.67E-05mmHg at 25°C
• Refractive Index: 1.6
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 13.99±0.10(Predicted)
• CAS DataBase Reference: (4-PYRID-4-YLPHENYL)METHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: (4-PYRID-4-YLPHENYL)METHANOL(217192-22-8)
• EPA Substance Registry System: (4-PYRID-4-YLPHENYL)METHANOL(217192-22-8)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22-37/38-41
• Safety Statements: 26-39
• Hazardous Substances Data: 217192-22-8(Hazardous Substances Data)

Usage

General Description

(4-Pyrid-4-ylphenyl)methanol is a chemical compound with the molecular formula C12H11NO. It is a white solid that is soluble in organic solvents and is commonly used as a reagent in organic synthesis. (4-PYRID-4-YLPHENYL)METHANOL has a pyridine ring and a phenyl group, with the hydroxyl group attached to the phenyl ring. (4-Pyrid-4-ylphenyl)methanol is often used in the preparation of various pharmaceuticals, agrochemicals, and materials science research. It is also a common building block in the synthesis of organic compounds due to its versatile reactivity.

InChI:InChI=1/C12H11NO/c14-9-10-1-3-11(4-2-10)12-5-7-13-8-6-12/h1-8,14H,9H2

Upstream product

• 1120-87-2 4-bromopyridin 
• 87736-74-1 4-(tert-butyldimethylsiloxymethyl)bromobenzene 
• 541-41-3 chloroformic acid ethyl ester 
• 99163-12-9 4-(pyridin-4-yl)benzaldehyde 
• 4385-76-6 4-(4-pyridinyl)benzoic acid 
• 1692-15-5 4-pyridylboronic acid 
• 873-76-7 para-Chlorobenzyl alcohol 
• 873-75-6 4-bromobenzenemethanol 
• 181219-01-2 4-pyridineboronic acid pinacol ester 

Downstream Products

• 1204185-08-9 4-[4-(chloromethyl)phenyl]pyridine hydrochloride 
• 1312700-65-4 [4-(4-(hydroxymethyl)phenylpyridinium)ethylbromide][OTf] 
• 1141447-96-2 4-(4-(chloromethyl)phenyl)pyridine 
• 1007-48-3 4-acetoxymethylpyridine 

Relevant articles and documents

PYRROLIDINE GLYCOSIDASE INHIBITORS

Compounds of formula (I) wherein A, W, R3b, Z and p have the meaning according to the claims can be employed, inter alia, for the treatment of tauopathies and Alzheimer's disease.

CARBAMATE DERIVATIVES OF LACTAM BASED N-ACYLETHANOLAMINE ACID AMIDASE (NAAA) INHIBITORS

Described herein are compounds and pharmaceutical compositions which inhibit N-acylethanolamine acid amidase (NAAA). Described herein are methods for synthesizing the compounds set forth herein and methods for formulating these compounds as pharmaceutical compositions which include these compounds. Also described herein are methods of inhibiting NAAA in order to sustain the levels of palmitoylethanolamide (PEA) and other N-acylethanolamines (NAE) that are substrates for NAAA, in conditions characterized by reduced concentrations of NAE. Also, described here are methods of treating and ameliorating pain, inflammation, inflammatory diseases, and other disorders in which modulation of fatty acid ethanolamides is clinically or therapeutically relevant or in which decreased levels of NAE are associated with the disorder.

Substituted (aminoiminomethyl or aminomethyl) dihydrobenzofurans and benzopyrans

This invention is directed to substituted (aminoiminomethyl or aminomethyl) dihydrobenzofurans and benzopyrans that inhibit Factor Xa, pharmaceutical compositions comprising these compounds and their use for inhibiting Factor Xa or treating pathological conditions in a patient that may be ameliorated by administration of such compounds. This invention is also is also directed to substituted (aminoiminomethyl or aminomethyl) dihydrobenzofurans and benzopyrans which directly inhibit both Factor Xa and Factor IIa (thrombin), to pharmaceutical compositions comprising these compounds, to intermediates useful for preparing these compounds and to a method of simultaneously directly inhibiting both Factor Xa and Factor IIa (thrombin).