217314-30-2

Basic information

• Product Name: 1H-Pyrrole, 1-(2-fluoro-4-iodophenyl)-2,5-dimethyl-
• CAS NO: 217314-30-2
• Molecular Formula: C12H11FIN
• Molecular Weight: 315.129
• Mol File: 217314-30-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1H-Pyrrole, 1-(2-fluoro-4-iodophenyl)-2,5-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrole, 1-(2-fluoro-4-iodophenyl)-2,5-dimethyl-(217314-30-2)
• EPA Substance Registry System: 1H-Pyrrole, 1-(2-fluoro-4-iodophenyl)-2,5-dimethyl-(217314-30-2)

Safety Data

• Hazardous Substances Data: 217314-30-2(Hazardous Substances Data)

Usage

Molecular structure

A pyrrole derivative with two methyl groups, a fluorine atom, and an iodine atom attached to a phenyl group.

Type of compound

A heterocyclic compound commonly found in naturally occurring substances and synthetic drugs.

Unique properties

The presence of the fluorine and iodine atoms on the phenyl group, as well as the methyl groups on the pyrrole ring, give the molecule unique properties.

Potential biological activities

The specific arrangement of atoms in the molecule may result in potential pharmacological effects that could be beneficial for drug development.

Possible use in medicinal chemistry

Further research into the properties and potential uses of 1H-Pyrrole, 1-(2-fluoro-4-iodophenyl)-2,5-dimethylmay be warranted for its potential use in pharmaceutical development.

Upstream product

• 29632-74-4 2-fluro-4-iodoaniline 
• 110-13-4 2,5-hexanedione 

Downstream Products

• 217314-31-3 1-(2-fluoro-4-methoxyphenyl)-2,5-dimethyl-1H-pyrrole 
• 630413-23-9 1-[2-fluoro-4-(4-fluoro-benzyloxy)-phenyl]-2,5-dimethyl-1H-pyrrole 
• 458-52-6 2-fluoro-4-(methoxy)aniline 

Relevant articles and documents

N-acylamino benzyl ether derivatives

This invention relates to N-acylamino aryl derivatives of the formula 1where R1, R21, R22, R23, R3, R4, R5 R6, R7, R8, R, and n are as defined herein and where X is —CHRO, —OCHR—, —CH2S—, —SCH2—, —CH2CH2—, —CH=CH— or —C≡C—. The compounds of the invention are selective monoamine oxidase B inhibitors, and they are therefore useful in the treatment of diseases mediated by monoamine oxidase B, for example, for the treatment of Alzheimer's disease or senile dementia.

Ullman methoxylation in the presence of a 2,5-dimethylpyrrole-blocked aniline: Preparation of 2-fluoro-4-methoxyaniline [ benzenamine, 2-fluoro-4-methoxy- ]

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2,5-dimethylpyrrole protection facilitates copper(I)-mediated methoxylations of aryl iodides in the presence of anilines

Converting iodoanilines to the corresponding 2,5-dimethylpyrroles was found to facilitate CuCI-mediated methoxide substitution. Examples with ortho-, meta-, or para-relationships between the iodide and aniline are presented. Several other aniline blocking groups were investigated and found not to be successful in this sequence.