21741-37-7

Basic information

• Product Name: 3-CYCLOPROPYL-2-METHYL-3-OXO-PROPIONIC ACID ETHYL ESTER
• Synonyms: 3-CYCLOPROPYL-2-METHYL-3-OXO-PROPIONIC ACID ETHYL ESTER
• CAS NO: 21741-37-7
• Molecular Formula: C9H14O3
• Molecular Weight: 170.21
• Mol File: 21741-37-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 225.5°Cat760mmHg
• Flash Point: 90.6°C
• Appearance: /
• Density: 1.102g/cm³
• Vapor Pressure: 0.0859mmHg at 25°C
• Refractive Index: 1.472
• PKA: 11.90±0.20(Predicted)
• CAS DataBase Reference: 3-CYCLOPROPYL-2-METHYL-3-OXO-PROPIONIC ACID ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 3-CYCLOPROPYL-2-METHYL-3-OXO-PROPIONIC ACID ETHYL ESTER(21741-37-7)
• EPA Substance Registry System: 3-CYCLOPROPYL-2-METHYL-3-OXO-PROPIONIC ACID ETHYL ESTER(21741-37-7)

Safety Data

• Hazardous Substances Data: 21741-37-7(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H14O3/c1-3-12-9(11)6(2)8(10)7-4-5-7/h6-7H,3-5H2,1-2H3

Upstream product

• 74-88-4 methyl iodide 
• 24922-02-9 Ethyl 3-cyclopropyl-3-oxopropionate 

Relevant articles and documents

MODULATORS OF GLUCOCORTICOID RECEPTOR, AP-1, AND/OR NF-kB ACTIVITY AND USE THEREOF

Non-steroidal compounds are provided which are useful in treating diseases associated with modulation of the glucocorticoid receptor, AP-1, and/or NF-?B activity including obesity, diabetes, inflammatory and immune diseases, and have the structure of formula (I) or an enantiomer, a diastereomer, a pharmaceutically acceptable salt, or hydrate thereof, where J is selected from NR1 or C(R4)(R4a); K is selected from NR2 or C(R5)(R5a); L is selected from NR3 or C(R6)(R6a); and A, X, Y, R1, R2, R3, R4, R4a, R5, R5a, R6, R6a, R8, R10, R11, and n are defined herein. Also provided are pharmaceutical compositions and methods of treating obesity, diabetes and inflammatory or immune associated diseases comprising said compounds.