217473-33-1

Basic information

• Product Name: 4-((Z)-1-Cyclohexylamino-3-imidazol-1-yl-3-oxo-propenyl)-benzoic acid ethyl ester
• Synonyms: 4-((Z)-1-Cyclohexylamino-3-imidazol-1-yl-3-oxo-propenyl)-benzoic acid ethyl ester
• CAS NO: 217473-33-1
• Molecular Weight: 367.448
• Mol File: 217473-33-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-((Z)-1-Cyclohexylamino-3-imidazol-1-yl-3-oxo-propenyl)-benzoic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-((Z)-1-Cyclohexylamino-3-imidazol-1-yl-3-oxo-propenyl)-benzoic acid ethyl ester(217473-33-1)
• EPA Substance Registry System: 4-((Z)-1-Cyclohexylamino-3-imidazol-1-yl-3-oxo-propenyl)-benzoic acid ethyl ester(217473-33-1)

Safety Data

• Hazardous Substances Data: 217473-33-1(Hazardous Substances Data)

Upstream product

• 530-62-1 1,1'-carbonyldiimidazole 

Downstream Products

• 38430-55-6 ethyl-4-acetylbenzoate 

Relevant articles and documents

Synthesis and reactivity of new β-enamino acid derivatives: A simple and general approach to β-enamino esters and thioesters

A new strategy has been developed for the synthesis of several β- enamino acid derivatives. N,N'-Carbonyldiimidazole has been used as C- acylating agent of methyl ketimines, providing a direct and simple route to new β-enamino carbonyl imidazole derivatives 2. These derivatives 2 were cleanly and efficiently transformed into β-enamino esters 4 (X = O) and thioesters 4 (X = S) by reaction with a great variety of alcohols and thiols, including tertiary ones. Alternative and complementary routes to compounds 4 were also investigated. In addition, β-keto esters 6 have been obtained by mild acid hydrolysis of β-enamino esters 4.