217475-21-3

Basic information

• Product Name: 2''-3''-di-O-benzyletoposide
• Synonyms: 2''-3''-di-O-benzyletoposide
• CAS NO: 217475-21-3
• Molecular Weight: 768.815
• Mol File: 217475-21-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2''-3''-di-O-benzyletoposide(CAS DataBase Reference)
• NIST Chemistry Reference: 2''-3''-di-O-benzyletoposide(217475-21-3)
• EPA Substance Registry System: 2''-3''-di-O-benzyletoposide(217475-21-3)

Safety Data

• Hazardous Substances Data: 217475-21-3(Hazardous Substances Data)

Upstream product

• 6559-91-7 4'-demethylepipodophyllotoxin 
• 170078-65-6 4,6-O-ethylidene-2,3-O-dibenzyl-D-glucose 

Downstream Products

• 33419-42-0 etoposide 

Relevant articles and documents

A crystallization-induced stereoselective glycosidation reaction in the synthesis of the anticancer drug etoposide.

The anticancer drug etoposide, 1, is prepared in 79% overall yield from readily available 4'-demethyl-4-epipodophyllotoxin, 3, and 4, 6-O-ethylidene-2,3-O-dibenzyl-D-glucose, 4, via a crystallization-induced stereoselective glycosidation reaction followed by catalytic hydrogenation.