21777-85-5

Basic information

• Product Name: Benzene, (cyclopropylethynyl)-
• CAS NO: 21777-85-5
• Molecular Formula: C11H10
• Molecular Weight: 142.2
• Mol File: 21777-85-5.mol
• Article Data: 36

Chemical Properties

• CAS DataBase Reference: Benzene, (cyclopropylethynyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, (cyclopropylethynyl)-(21777-85-5)
• EPA Substance Registry System: Benzene, (cyclopropylethynyl)-(21777-85-5)

Safety Data

• Hazardous Substances Data: 21777-85-5(Hazardous Substances Data)

Upstream product

• 127462-01-5 (E)-1-cyclopropyl-1-phenylseleninyl-2-phenylethene 
• 591-50-4 iodobenzene 
• 6746-94-7 Cyclopropylacetylene 
• 4333-56-6 cyclopropyl bromide 
• 536-74-3 phenylacetylene 
• 66003-78-9 triphenylsulfonium trifluoromethanesulfonate 
• 945-51-7 1,1'-sulfinylbisbenzene 
• 62-53-3 aniline 
• 369-57-3 benzenediazonium tetrafluoroborate 
• 13633-26-6 4-phenylbut-1-en-3-yne 
• 1372474-95-7 sodium 3-(N-methyl-N-nitrososulfamoyl)benzoate 
• 35200-90-9 5-cyclopropyl-5-phenyl-oxazolidin-2-one 
• 3481-02-5 cyclopropyl phenyl ketone 
• 57951-63-0 1-(phenylethynyl)cyclopropan-1-ol 

Downstream Products

• 85157-75-1 2,5-Dichlor-1-phenyl-2-penten 
• 85157-71-7 (E)-1-Chlor-1-cyclopropyl-2-phenylethen 
• 85157-72-8 (Z)-1-Chlor-1-cyclopropyl-2-phenylethen 
• 85157-70-6 (E)-1-Chlor-2-cyclopropyl-1-phenylethen 
• 85157-73-9 (Z)-1-Chlor-2-cyclopropyl-1-phenylethen 

Relevant articles and documents

Reaction of Alkynyl- And Alkenyltrifluoroborates with Propargyldicobalt Cations: Alkynylation, Alkenylation, and Cyclopropanation Product Pathways

The Lewis acid-mediated Nicholas reactions of propargyl acetate–Co2(CO)6 complexes with a series of potassium alkynyltrifluoroborates and potassium alkenyltrifluoroborates are described. Alkynyltrifluoroborates directly alkynylate the intermediate propargyldicobalt cations. In contrast, alkenyltrifluoroborates proceed through one of the three modes of dominant reactivity: C-2-substituted alkenyltrifluorobrates directly alkenylate, predominantly with the retention of stereochemistry. C-1-substituted alkenyltrifluoroborates alkenylate at C-2. Potassium vinyltrifluoroborate incorporates a cyclopropane at the site propargyl to alkynedicobalt. Computational analysis of these systems explains the differential modes of reactivity of alkenyltrifluoroborates and outlines the probable mechanisms for the formation of each product.

1- And 2-Azetines via Visible Light-Mediated [2 + 2]-Cycloadditions of Alkynes and Oximes

Azetines, four-membered unsaturated nitrogen-containing heterocycles, hold great potential for drug design and development but remain underexplored due to challenges associated with their synthesis. We report an efficient, visible light-mediated approach

Phosphorus(III)-Mediated, Tandem Deoxygenative Geminal Chlorofluorination of 1,2-Diketones

Tetrasubstituted carbon containing two different halogen substituents was constructed in a single-step operation by utilizing the carbene-like reactivity of dioxaphospholene through the tandem reaction of electrophilic and nucleophilic halogenating reagents. It was crucial to devise non-dealkylatable phosphoramidite, which enabled the efficient formation of geminal chlorofluorides from various 1,2-diketones with (PhSO2)2NF and n-Bu4NCl. In addition, selective functionalization of the chlorine substituent was demonstrated, and the absence of halogen scrambling was confirmed.