217816-54-1

Basic information

• Product Name: 3-bromo-2-fluoro-6-iodobenzoicacid
• Synonyms: 3-bromo-2-fluoro-6-iodobenzoicacid
• CAS NO: 217816-54-1
• Molecular Formula: C7H3BrFIO2
• Molecular Weight: 344.907
• Mol File: 217816-54-1.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 3-bromo-2-fluoro-6-iodobenzoicacid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-bromo-2-fluoro-6-iodobenzoicacid(217816-54-1)
• EPA Substance Registry System: 3-bromo-2-fluoro-6-iodobenzoicacid(217816-54-1)

Safety Data

• Hazardous Substances Data: 217816-54-1(Hazardous Substances Data)

Upstream product

• 124-38-9 carbon dioxide 
• 136434-77-0 4-bromo-3-fluoroiodobenzene 
• 348-54-9 2-Fluoroaniline 
• 29632-74-4 2-fluro-4-iodoaniline 

Relevant articles and documents

METALLO-BETA-LACTAMASE INHIBITORS AND METHODS OF USE THEREOF

The present invention relates to metallo-β-lactamase inhibitor compounds of Formula (I) and pharmaceutically acceptable salts thereof, wherein Z, RA, X1, X2 and R1 are as defined herein. The present invention also relates to compositions which comprise a metallo-β-lactamase inhibitor compound of the invention or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, optionally in combination with a beta lactam antibiotic and/or a beta-lactamase inhibitor. The invention further relates to methods for treating a bacterial infection comprising administering to a patient a therapeutically effective amount of a compound of the invention, in combination with a therapeutically effective amount of one or more β-lactam antibiotics and optionally in combination with one or more beta-lactamase inhibitor compounds. The compounds of the invention are useful in the methods described herein for overcoming antibiotic resistance.

ISOQUINOLINE DERIVATIVES AS PERK INHIBITORS

The invention is directed to substituted isoquinoline derivatives and uses thereof. Specifically, the invention is directed to compounds according to Formula I and the use of compounds of Formula (I) in treating disease states: (I) wherein R1,

METALLO-BETA-LACTAMASE INHIBITORS

The present invention relates to compounds of formula I that are metallo-β-lactamase inhibitors, the synthesis of such compounds, and the use of such compounds for use with β-lactam antibiotics for overcoming resistance.