218139-11-8Relevant articles and documents
Importance of the proximity and orientation of ligand-linkage to the design of cinnamate-GW9662 hybrid compounds as covalent PPAR agonists
Utsugi, Yuki,Kobuchi, Hirona,Kawamura, Yukio,Atito, Ahmed Salahelden Aboelhamd,Nagao, Masaya,Isoda, Hiroko,Miyamae, Yusaku
, (2019)
Covalent agonists of PPAR cause unique receptor conformational changes and behave as selective PPAR modulators, whereas there are few covalent agonists other than endogenous unsaturated fatty acids metabolites. Previously, we established a cell-based stra
Thiazolidinedione, oxazolidinedione and oxadiazolidinedione derivatives
-
, (2008/06/13)
Novel thiazolidinedione, oxazolidinedione and oxadiazolidinedione derivatives, process for their manufacture, pharmaceutical preparations containing them and the use of the compounds in conditions associated with insulin resistance.