218157-36-9

Basic information

• Product Name: N'-(2-phenoxypyridine-3-carbonyl)-3-(trifluoromethyl)benzhydrazide
• CAS NO: 218157-36-9
• Molecular Weight: 401.345
• Mol File: 218157-36-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N'-(2-phenoxypyridine-3-carbonyl)-3-(trifluoromethyl)benzhydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: N'-(2-phenoxypyridine-3-carbonyl)-3-(trifluoromethyl)benzhydrazide(218157-36-9)
• EPA Substance Registry System: N'-(2-phenoxypyridine-3-carbonyl)-3-(trifluoromethyl)benzhydrazide(218157-36-9)

Safety Data

• Hazardous Substances Data: 218157-36-9(Hazardous Substances Data)

Upstream product

• 51362-49-3 2-phenoxypyridine-3-carbonyl chloride 
• 22227-25-4 3-(trifluoromethyl)benzene-1-carbohydrazide 

Relevant articles and documents

Substituted N'-(arylcarbonyl)-benzhydrazides, N'-(arylcarbonyl)-benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof

The present invention is directed to substituted N′-(arylcarbonyl)-benzhydrazides, N′-(arylcarbonyl)-benzylidene-hydrazides and analogs thereof, represented by the Formulae I and II: wherein Ar1, Ar2, and R1-R2 are defined herein. The present invention also relates to the discovery that compounds having Formulae I and II are activators of caspases and inducers of apoptosis. Therefore, the activators of caspases and inducers of apoptosis of this invention may be used to induce cell death in a variety of clinical conditions in which uncontrolled growth and spread of abnormal cells occurs.