21844-69-9

Basic information

• Product Name: N-[(Benzyloxy)carbonyl]-L-valine 4-pyridylmethyl ester
• Synonyms: N-[(Benzyloxy)carbonyl]-L-valine 4-pyridylmethyl ester
• CAS NO: 21844-69-9
• Molecular Formula: C₁₉H₂₂N₂O₄
• Molecular Weight: 342.39
• Mol File: 21844-69-9.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-[(Benzyloxy)carbonyl]-L-valine 4-pyridylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-[(Benzyloxy)carbonyl]-L-valine 4-pyridylmethyl ester(21844-69-9)
• EPA Substance Registry System: N-[(Benzyloxy)carbonyl]-L-valine 4-pyridylmethyl ester(21844-69-9)

Safety Data

• Hazardous Substances Data: 21844-69-9(Hazardous Substances Data)

Upstream product

• 1149-26-4 (S)-N-(benzyloxycarbonyl)valine 
• 1822-51-1 4-picolylchloride hydrochloride 

Downstream Products

• 1149-26-4 (S)-N-(benzyloxycarbonyl)valine 

Relevant articles and documents

Novel facilitation of peptide synthesis

THE solid phase method of synthesizing peptides1, in which the carbon-terminal residue is first esterified to a hydroxymethylpolystyrene resin, has been used successfully for the rapid synthesis in high yield of peptides which can be purified after removal from the resin2. If such a procedure, which omits the purification of intermediates, is to yield a homogeneous product without further purification, every stage must proceed to completion. For example, if 0.5 per cent of the amino-groups remain unacylated after each coupling, then after one hundred stages the product will contain only 61 per cent of the required peptide, the remainder being peptides with closely similar but defective sequences. It is a serious disadvantage of the solid phase method that one of the reactants is polymeric, making it difficult to force reactions to completion.