21851-78-5

Basic information

• Product Name: Benzene, 1-(3-bromopropyl)-2-methyl-
• CAS NO: 21851-78-5
• Molecular Formula: C10H13Br
• Molecular Weight: 213.117
• Mol File: 21851-78-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzene, 1-(3-bromopropyl)-2-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-(3-bromopropyl)-2-methyl-(21851-78-5)
• EPA Substance Registry System: Benzene, 1-(3-bromopropyl)-2-methyl-(21851-78-5)

Safety Data

• Hazardous Substances Data: 21851-78-5(Hazardous Substances Data)

Upstream product

• 1587-04-8 1-methyl-2-(2-propenyl)-benzene 
• 22084-89-5 3-(2-methylphenyl)propanoic acid 
• 104750-61-0 ethyl 3-(o-tolyl)propanoate 
• 95-46-5 2-methylphenyl bromide 
• 109-64-8 1,3-dibromo-propane 
• 38256-57-4 1-(bromomethyl)-2-(3-bromopropyl)benzene 
• 24393-48-4 2-methyl-cinnamic acid ethyl ester 
• 21851-77-4 1-(3-Brom-propyl)-2-triphenylphosphoniomethyl-benzolbromid 

Downstream Products

• 6939-35-1 5-methyl-1-tetralone 
• 859809-70-4 4-o-tolyl-butyryl chloride 
• 1093172-45-2 [2,2-dimethyl-5-(2-{4-[3-(2-methylphenyl)propoxy]-3-trifluoromethylphenyl}ethyl)-1,3-dioxan-5-yl]carbamic acid t-butyl ester 
• 6943-79-9 4-(2-methylphenyl)butanoic acid 

Relevant articles and documents

Air-Stable PdI Dimer Enabled Remote Functionalization: Access to Fluorinated 1,1-Diaryl Alkanes with Unprecedented Speed

While remote functionalization via chain walking has the potential to enable access to molecules via novel disconnections, such processes require relatively long reaction times and can be in need of elevated temperatures. This work features a remote arylation in less than 10 min reaction time at room temperature over a distance of up to 11 carbons. The unprecedented speed is enabled by the air-stable PdI dimer [Pd(μ-I)(PCy2tBu)]2, which in contrast to its PtBu3 counterpart does not trigger direct coupling at the initiation site, but regioconvergent and chemoselective remote functionalization to yield valuable fluorinated 1,1-diaryl alkanes. Our combined experimental and computational studies rationalize the origins of switchability, which are primarily due to differences in dispersion interactions.

DIARYL ETHERS AS OPIOID RECEPTOR ANTAGONIST

A compound of the formula (I) wherein the variables X1 to X10, R1 to R7 including R3', E, v, y, z, A and B are as described, or a pharmaceutically acceptable salt, solvate, enantiomer, racemate, diastereomer or mixtures thereof, useful for the treatment, prevention or amelioration of obesity and Related Diseases is disclosed.