21867-81-2Relevant articles and documents
Synthesis and structure-activity relationships of 1-aralkyl-4- benzylpiperidine and 1-aralkyl-4-benzylpiperazine derivatives as potent σ ligands
Costantino, Luca,Gandolfi, Francesca,Sorbi, Claudia,Franchini, Silvia,Prezzavento, Orazio,Vittorio, Franco,Ronsisvalle, Giuseppe,Leonardi, Amedeo,Poggesi, Elena,Brasili, Livio
, p. 266 - 273 (2007/10/03)
In the attempt to define more accurately structure-affinity relationships for σ1 and σ2 ligands, we synthesized and tested on σ subtype receptors a series of aralkyl derivatives of 4-benzylpiperidine, in which the effect of modificat