2187-27-1

Basic information

• Product Name: Acetamide, N-(1-hydroxy-2-oxo-2-phenylethyl)-
• CAS NO: 2187-27-1
• Molecular Formula: C10H11NO3
• Molecular Weight: 193.202
• Mol File: 2187-27-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Acetamide, N-(1-hydroxy-2-oxo-2-phenylethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, N-(1-hydroxy-2-oxo-2-phenylethyl)-(2187-27-1)
• EPA Substance Registry System: Acetamide, N-(1-hydroxy-2-oxo-2-phenylethyl)-(2187-27-1)

Safety Data

• Hazardous Substances Data: 2187-27-1(Hazardous Substances Data)

Upstream product

• 60-35-5 acetamide 
• 1075-06-5 2,2-dihydroxy-1-phenyl-ethanone 

Downstream Products

• 22903-00-0 3-(methylthio)-4-phenyl-1H-pyrrole-2,5-dione 
• 79848-81-0 N-acetyl-2-oxo-2-phenylacetamide 
• 97166-38-6 -benzol 
• 3893-31-0 N-(2-oxo-1,2-diphenylethyl)acetamide 
• 14224-99-8 2-methyl-4,5-diphenyloxazole 
• 97166-37-5 benzol 
• 51626-12-1 4-chloro-2-methyl-5-phenyloxazole 
• 2818-82-8 2-methyl-4,5-diphenyl-1H-imidazole 

Relevant articles and documents

Convergent integration of three self-sorting domino sequences: Three-component direct synthesis of 3-methylthio-4-aryl-maleimides from methyl ketones with acetonitrile and DMSO

An I2-promoted three-component coupling reaction was described for the construction of 3-(methylthio)-4-aryl-1H-pyrrole-2,5-diones from methyl ketones with acetonitrile and DMSO. This transformation involved the in situ generation and application of α-ketoimides. Furthermore, DMSO was converted to DMS in situ, which subsequently served as a methylthiolation reagent in the reaction. To the best of our knowledge, this protocol provided the first known example of convergent integration of three self-sorting domino sequences.