218768-05-9

Basic information

• Product Name: C₁₂H₁₅NO₂
• Synonyms: C₁₂H₁₅NO₂
• CAS NO: 218768-05-9
• Molecular Weight: 205.257
• Mol File: 218768-05-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₁₂H₁₅NO₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₂H₁₅NO₂(218768-05-9)
• EPA Substance Registry System: C₁₂H₁₅NO₂(218768-05-9)

Safety Data

• Hazardous Substances Data: 218768-05-9(Hazardous Substances Data)

Upstream product

• 5468-37-1 2-aminoacetophenone hydrochloride 
• 79-30-1 isobutyryl chloride 

Downstream Products

• 218768-02-6 N-(2-hydroxy-2-phenyl-ethyl)-2-methyl-propanamide 

Relevant articles and documents

Kinetic Resolution of 2-N-Acylamido Tertiary Allylic Alcohols: Asymmetric Synthesis of Oxazolines

A series of cyclohexyl-fused SPINOL-derived phosphoric acids (Cy-SPA) have been developed to catalyze the kinetic resolution of 2-N-acylamido tertiary allylic alcohols, providing access to chiral oxazolines bearing C-2 alkyl substituents with high enantioselectivities (with s-factors up to 153). Gram-scale reaction with 1 mol% catalyst loading and transformations of the chiral products demonstrates the value of these methods. (Figure presented.).