21889-13-4

Basic information

• Product Name: 1,3-Indandione, 2- (4-dimethylaminophenylmethylene)
• Synonyms: 1,3-Indandione, 2- (4-dimethylaminophenylmethylene);2-[[4-(Dimethylamino)phenyl]methylene]-1H-indene-1,3(2H)-dione;2-[4-(Dimethylamino)benzylidene]-1,3-indandione;2-[4-(Dimethylamino)benzylidene]-1H-indene-1,3(2H)-dione;2-[4-(Dimethylamino)benzylidene]-2H-indene-1,3-dione
• CAS NO: 21889-13-4
• Molecular Formula: C₁₈H₁₅NO₂
• Molecular Weight: 277.32
• Mol File: 21889-13-4.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 492.3°Cat760mmHg
• Flash Point: 231.7°C
• Appearance: /
• Density: 1.276g/cm³
• Vapor Pressure: 7.78E-10mmHg at 25°C
• Refractive Index: 1.696
• CAS DataBase Reference: 1,3-Indandione, 2- (4-dimethylaminophenylmethylene)(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Indandione, 2- (4-dimethylaminophenylmethylene)(21889-13-4)
• EPA Substance Registry System: 1,3-Indandione, 2- (4-dimethylaminophenylmethylene)(21889-13-4)

Safety Data

• Hazardous Substances Data: 21889-13-4(Hazardous Substances Data)

Usage

General Description

1,3-Indandione, 2-(4-dimethylaminophenylmethylene) is a chemical compound that belongs to the class of indandione derivatives. It is commonly used in organic synthesis as a reagent for the synthesis of various compounds. 1,3-Indandione, 2- (4-dimethylaminophenylmethylene) is known for its diverse applications, including use in the production of pharmaceuticals, dyes, and other organic chemicals. It has also been investigated for its potential biological activities, particularly as an antioxidant and anti-inflammatory agent. Additionally, it has been studied for its potential use in the treatment of various diseases and disorders, making it a versatile and valuable compound in the field of organic chemistry and pharmaceutical research.

InChI:InChI=1/C18H15NO2/c1-19(2)13-9-7-12(8-10-13)11-16-17(20)14-5-3-4-6-15(14)18(16)21/h3-11H,1-2H3

Upstream product

• 606-23-5 1H-indene-1,3(2H)-dione 
• 100-10-7 4-dimethylamino-benzaldehyde 
• 889-37-2 N,N-dimethyl-4-((phenylimino)methyl)aniline 
• 84-66-2 Diethyl phthalate 

Downstream Products

• 49764-75-2 (4-N,N-dimethylaminophenyl)(1,3-dioxo-2-indanylidene)acetonitrile 
• 967-04-4 2-(4-dimethylamino-benzyl)-indan-1,3-dione 
• 88874-07-1 3'-(4-Dimethylaminophenyl)-1,3-dioxo-indan-2-spiro-2'-oxiran 
• 2471-89-8 2-[1-(4-Dimethylamino-phenyl)-2-nitro-ethyl]-indan-1,3-dione 
• 1093169-03-9 4-(1-cyano-2-(4-(dimethylamino)phenyl)-2-(1,3-dioxo-2,3-dihydro-1H-inden-2-yl)ethyl)-benzonitrile 
• 1057717-27-7 C₃₂H₂₅N₂O₄S^(1-)*K⁽¹⁺⁾ 
• 1259377-22-4 4-(2-(4-(dimethylamino)phenyl)-1',3'-dioxo-1',3'-dihydrospiro[cyclopropane-1,2'-inden]-3-yl)benzonitrile 

Relevant articles and documents

T-shaped D?π?A?(π?A)2 chromophores with two auxiliary electron acceptors

A series of tripodal push-pull chromophores based on central indan-1,3-dione scaffold has been designed and synthesized by Knoevenagel condensation and Pd-catalyzed Suzuki-Miyaura cross-coupling reaction. Target molecules possess D?π?A?(π?A)2 e

Selected drug-likeness properties of 2-arylidene-indan-1,3-dione derivatives—chemical compounds with potential anti-cancer activity

2-Arylidene-indan-1,3-done derivatives have very different properties, thanks to which they find various applications in science, medicine, and industry. Selected derivatives show antivi-ral, antibacterial, and anti-inflammatory activity. This paper prese

Zirconium catalyzed synthesis of 2-arylidene Indan-1,3-diones and evaluation of their inhibitory activity against NS2B-NS3 WNV protease

A simple and efficient Knoevenagel procedure for the synthesis of 2-arylidene indan-1,3-diones is herein reported. These compounds were prepared via ZrOCl2·8H2O catalyzed reactions of indan-1,3-dione with several aromatic aldehydes and using water as the