218911-25-2

Basic information

• Product Name: 1-[4-(4-chlorobenzyl)piperazin-1-yl]-3-phenylpropan-2-one
• Synonyms: 1-[4-(4-chlorobenzyl)piperazin-1-yl]-3-phenylpropan-2-one
• CAS NO: 218911-25-2
• Molecular Weight: 342.868
• Mol File: 218911-25-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-[4-(4-chlorobenzyl)piperazin-1-yl]-3-phenylpropan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[4-(4-chlorobenzyl)piperazin-1-yl]-3-phenylpropan-2-one(218911-25-2)
• EPA Substance Registry System: 1-[4-(4-chlorobenzyl)piperazin-1-yl]-3-phenylpropan-2-one(218911-25-2)

Safety Data

• Hazardous Substances Data: 218911-25-2(Hazardous Substances Data)

Upstream product

• 937-38-2 1-chloro-3-phenylpropan-2-one 
• 23145-88-2 1-[(4-chlorophenyl)methyl]piperazine 
• 77290-30-3 tert-butyl 4-(4-chlorobenzyl)piperazine-1-carboxylate 
• 104-83-6 1-Chloro-4-(chloromethyl)benzene 

Relevant articles and documents

Substituted pyrazoles as novel selective ligands for the human dopamine D4 receptor

Two novel series of 3-(heterocyclylmethyl)pyrazoles have been synthesised and evaluated as ligands for the human dopamine D4 receptor. Compounds in series I (exemplified by 8k) have a phenyl ring joined to the 4-position of the pyrazole while those in series II (exemplified by 15j) have a 5-phenyl ring linked by a saturated chain to the 4-position of the pyrazole. Both series supplied compounds with excellent affinity for the human D4 and good selectivity over other dopamine receptors. Excellent selectivity over calcium, sodium, and potassium ion channels was also achieved. Copyright (C) 1997 Elsevier Science Ltd.