21900-50-5

Basic information

• Product Name: Benzoyl chloride, 2-chloro-5-methyl-
• CAS NO: 21900-50-5
• Molecular Formula: C8H6Cl2O
• Molecular Weight: 189.041
• Mol File: 21900-50-5.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzoyl chloride, 2-chloro-5-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoyl chloride, 2-chloro-5-methyl-(21900-50-5)
• EPA Substance Registry System: Benzoyl chloride, 2-chloro-5-methyl-(21900-50-5)

Safety Data

• Hazardous Substances Data: 21900-50-5(Hazardous Substances Data)

Upstream product

• 106-43-4 para-chlorotoluene 
• 6342-60-5 2-chloro-5-methyl-benzoic acid 

Downstream Products

• 99520-00-0 3-(4-chlorobenzoyl)-4-chlorotoluene 
• 660417-31-2 C₁₀H₁₀Cl₂N₂O₂ 
• 107410-52-6 2-chloro-5-methyl-benzophenone 
• 55142-55-7 (3-Benzoyl-4-chloro-phenyl)-acetic acid 

Relevant articles and documents

PHARMACEUTICAL COMPOSITION AND APPLICATION REPLACING QUINOLONE DERIVATIVE, PHARMACEUTICAL ACCEPTABLE SALT, OR STEREOISOMER

Provided are a substituted quinolone derivative as shown by formula (I), or a pharmaceutically acceptable salt and a prodrug molecule thereof, and a pharmaceutical composition thereof, as well as the use of same in preparing drugs for the prevention and treatment of a tumor. The quinolone derivative, salt, prodrug molecule, and pharmaceutical composition thereof can be used as a protein kinase inhibitor, which is effective in inhibiting the activity of AXL protein kinase, and is capable of inhibiting the proliferation, migration and invasion of various tumor cells; and can be used in the preparation of anti-tumor drugs, especially drugs for treating hyperproliferative diseases such as a tumor in human beings and other mammals.

4-Oxo-1,4-dihydroquinoline-3-carboxamide Derivatives as New Axl Kinase Inhibitors

Axl is a new potential target for anticancer drug discovery. A series of 4-oxo-1,4-dihydroquinoline-3-carboxamides were designed and synthesized as highly potent Axl kinase inhibitors. One of the most promising compounds, 9im, tightly bound with Axl prote

NEW COMPOUNDS

The present invention relates to new compounds of formula (I), wherein P, Q, X1, X2, X3, X4, R, R1, R2, R3, R4, R5, R6, R7, m, n, o, p and q are defined as in any one of claims 1 to 12, a process for their preparation and new intermediates prepared therein, pharmaceutical formulations containing said compounds and to the use of said compounds in therapy.