21911-85-3

Basic information

• Product Name: methyl 3-(p-toluidino)propanoate
• Synonyms: methyl 3-(p-toluidino)propanoate
• CAS NO: 21911-85-3
• Molecular Weight: 193.246
• Mol File: 21911-85-3.mol
• Article Data: 21

Chemical Properties

• CAS DataBase Reference: methyl 3-(p-toluidino)propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3-(p-toluidino)propanoate(21911-85-3)
• EPA Substance Registry System: methyl 3-(p-toluidino)propanoate(21911-85-3)

Safety Data

• Hazardous Substances Data: 21911-85-3(Hazardous Substances Data)

Upstream product

• 106-49-0 p-toluidine 
• 292638-85-8 acrylic acid methyl ester 
• 959698-50-1 methyl 3-[N-(2-iodo-4-methylphenyl)-N-methylamino]propionate 

Downstream Products

• 18042-72-3 3-[(5-Chloro-2-diacetylamino-benzyl)-p-tolyl-amino]-propionic acid methyl ester 
• 101719-41-9 methyl N-tosyl-3-(4-methylanilino)propionate 
• 599-86-0 4-methyl-N-(4-methylphenyl)benzenesulfonamide 
• 1422186-25-1 1-tosyl-4,4,6-trimethyl-1,2,3,4-tetrahydroquinoline 
• 1422186-15-9 N-tosyl-4-(4-methylanilino)-2-methyl-2-butanol 
• 1274848-49-5 8-methyl-5-(3-nitrophenyl)-2,3-dihydro-1H-pyrrolo[3,2,1-ij]quinolin-1-one 
• 1274848-46-2 (8-methyl-5-p-tolyl-2,3-dihydro-1H-pyrrolo[3,2,1-ij]quinolin-1-one) 
• 1274848-28-0 6-methyl-8-((3-nitrophenyl)ethynyl)-2,3-dihydroquinolin-4(1H)-one 
• 1274848-26-8 6-methyl-8-(p-tolylethynyl)-2,3-dihydroquinolin-4(1H)-one 
• 36054-00-9 6-methyl-2,3-dihydroquinolin-4(1H)-one 
• 959698-47-6 methyl 3-[N-(2-iodo-4-methylphenyl)amino]propionate 
• 18221-78-8 3-[(2-Amino-5-chloro-benzyl)-p-tolyl-amino]-propionic acid 
• 18042-73-4 3-[(2-Acetylamino-5-chloro-benzyl)-p-tolyl-amino]-propionic acid 
• 35045-62-6 3-p-Tolylamino-propionic acid [1-(4-dimethylamino-phenyl)-meth-(E)-ylidene]-hydrazide 

Relevant articles and documents

HOTf-catalyzed intermolecular hydroamination reactions of alkenes and alkynes with anilines

Herein, the intermolecular hydroamination of alkenes and alkynes with anilines catalyzed by HOTf under mild conditions has been developed. This reaction provides one of the simplest alkene and alkyne addition methods and is an alternative to metal-catalyzed reactions. At the same time, the intramolecular hydroamination of alkynes with anilines proceeds smoothly to obtain quinolines. We found that this strategy is efficient in building complex structures from simple starting materials in an environmentally benign fashion.

Tetrahydroquinolines by lewis acid-promoted friedel-crafts cyclizations

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Ecofriendly and efficient procedure for hetero-Michael addition reactions with an acidic ionic liquid as catalyst and reaction medium

1-Methylimidazolium trifluoroacetate ([Hmim]-TFA) is reported as a cost-effective catalyst for a simple and environmentally benign hetero-Michael reaction. [Hmim]TFA works both as reaction medium and catalyst. The reaction is applicable to various aromatic sulfur and nitrogen nucleophiles. This method has advantages such as high yields, short reaction time, and simple workup. The catalyst could be recycled several times without any loss of activity.