21955-55-5Relevant articles and documents
A convenient and mild chromatography-free method for the purification of the products of Wittig and Appel reactions
Byrne, Peter A.,Rajendran, Kamalraj V.,Muldoon, Jimmy,Gilheany, Declan G.
supporting information; experimental part, p. 3531 - 3537 (2012/05/20)
A mild method for the facile removal of phosphine oxide from the crude products of Wittig and Appel reactions is described. Work-up with oxalyl chloride to generate insoluble chlorophosphonium salt (CPS) yields phosphorus-free products for a wide variety of these reactions. The CPS product can be further converted into phosphine.