21962-24-3Relevant articles and documents
Lewis,Hill
, p. 7458 (1969)
Enantioselective total synthesis of (-)-Clavosolide A and B
Son, Jung Beom,Kim, Si Nae,Kim, Na Yeong,Hwang, Min-Ho,Lee, Wonsun,Lee, Duck Hyung
scheme or table, p. 653 - 663 (2010/08/19)
Enantioselective total synthesis of (-)-clavosolide A and B was reported in full including the synthesis of proposed structure of (-)-clavosoldie A (1), revised structure of (-)-clavosoldie A (5), and revised structure of (-)-clavosoldie B (6). The relative and absolute stereochemistries of the natural products were confirmed unambiguously by comparing the optical rotation values and 1H and 13C NMR spectra of them.
A Convenient Method for the Preparation of Secondary Propargylic Ethers. The Reaction of Acetals with 1-Trimethylsilyl-1-alkynes Promoted by the Combined Use of Catalytic Amounts of Tin(IV) Chloride and Zinc Chloride
Hayashi, Masaji,Inubushi, Atsuro,Mukaiyama, Teruaki
, p. 4037 - 4042 (2007/10/02)
In the coexistence of catalytic amounts of SnCl4 and ZnCl2, acetals undergo a coupling with 1-trimethylsilylalkynes to give secondary propargilic ethers in good yields.Similarly, propargilic ethers are directly produced from aldehydes by the treatment with alkoxytrimethylsilanes and 1-trimethylsilylalkynes under the same conditions.This catalyst system also efficiently promotes aldol reaction of silyl enol ethers with acetals or aldehydes, and the Michael reaction of silyl enol ethers with α,β-unsaturated ketones.
