219648-29-0Relevant articles and documents
The synthesis of RNA containing the modified nucleotides N2- methylguanosine and N6,N6-dimethyladenosine
Rife, Jason P.,Cheng, Charles S.,Moore, Peter B.,Strobel, Scott A.
, p. 2281 - 2288 (2007/10/03)
The phosphoramidites of the naturally occurring modified nucleotides N2-methylguanosine and N6, N6-dimethyladenosine were synthesized and incorporated into short oligoribonucleotides. Described are the syntheses of the phosphoramidites and the procedures used to deprotect oligoribonucleotides in which the O6 of m2G is protected with a 2-(p- nitrophenyl)ethyl group.