21965-92-4Relevant articles and documents
Visible Light-Mediated Direct Decarboxylative C-H Functionalization of Heteroarenes
Garza-Sanchez, R. Aleyda,Tlahuext-Aca, Adrian,Tavakoli, Ghazal,Glorius, Frank
, p. 4057 - 4061 (2017/06/19)
The direct visible light-mediated C-H alkylation of heteroarenes using aliphatic carboxylic acids is reported. This mild method proceeds at low catalyst loadings (0.5 mol %) and has a high functional group tolerance and a broad substrate scope. Notably, f
Sunflow: Sunlight Drives Fast and Green Photochemical Flow Reactions in Simple Microcapillary Reactors – Application to Photoredox and H-Atom-Transfer Chemistry
Nauth, Alexander M.,Lipp, Alexander,Lipp, Benjamin,Opatz, Till
supporting information, p. 2099 - 2103 (2017/04/24)
“Sunflow“ – The combination of a microcapillary reactor in continuous flow mode with sunlight as the most sustainable energy source imaginable was applied to a range of photoredox and H-atom-transfer reactions making them both fast and green.
Transition-Metal-Free Decarboxylative Photoredox Coupling of Carboxylic Acids and Alcohols with Aromatic Nitriles
Lipp, Benjamin,Nauth, Alexander M.,Opatz, Till
, p. 6875 - 6882 (2016/08/16)
A transition-metal-free protocol for the redox-neutral light-induced decarboxylative coupling of carboxylic acids with (hetero)aromatic nitriles at ambient temperature is presented. A broad scope of acids and nitriles is accepted, and alcohols can be coupled in a similar fashion through their oxalate half esters. Various inexpensive sources of UV light and even sunlight can be used to achieve this C-C bond formation proceeding through a free radical mechanism.