219652-98-9Relevant articles and documents
Deoxynucleic alkyl thiourea compounds and uses thereof
-
, (2008/06/13)
The invention provides novel deoxynucleic alkyl thiourea (dNXt) oligonucleotide compounds for use in antisense or antigene therapy.
Positively charged deoxynucleic methylthioureas: Synthesis and binding properties of pentameric thymidyl methylthiourea
Arya, Dev P.,Bruice, Thomas C.
, p. 12419 - 12427 (2007/10/03)
The negatively charged phosphodiester linkages in DNA {-O(PO2-)O-} have been replaced by a novel methylthiourea {-NHC(=SMe+)NH-} backbone. The backbone is positively charged, achiral, and stable and can be easily synthesiz