219702-29-1

Basic information

• Product Name: Methyl 4-S-benzoyl-2,6-dideoxy-4-thio-3-O-(2,2,2-trifluoroethylsulfonyl)-α-D-arabino-hexopyranoside
• CAS NO: 219702-29-1
• Molecular Weight: 428.45
• Mol File: 219702-29-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Methyl 4-S-benzoyl-2,6-dideoxy-4-thio-3-O-(2,2,2-trifluoroethylsulfonyl)-α-D-arabino-hexopyranoside(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 4-S-benzoyl-2,6-dideoxy-4-thio-3-O-(2,2,2-trifluoroethylsulfonyl)-α-D-arabino-hexopyranoside(219702-29-1)
• EPA Substance Registry System: Methyl 4-S-benzoyl-2,6-dideoxy-4-thio-3-O-(2,2,2-trifluoroethylsulfonyl)-α-D-arabino-hexopyranoside(219702-29-1)

Safety Data

• Hazardous Substances Data: 219702-29-1(Hazardous Substances Data)

Upstream product

• 1648-99-3 2,2,2-Trifluoroethanesulfonyl chloride 
• 152870-51-4 methyl 4-S-benzoyl-2,6-dideoxy-4-thio-α-D-arabino-hexopyranoside 

Downstream Products

• 330450-36-7 Methyl 4-(3-O,4-S-dibenzoyl-2,6-dideoxy-4-thio-β-D-ribo-hexopyranosyloxyamino)-4,6-dideoxy-2-O-{4'-[N-ethyl-N-(fluoren-9-ylmethoxycarbonyl)amino]butyl}-α-D-glucopyranoside 
• 330450-30-1 3-O,4-S-Dibenzoyl-2,6-dideoxy-4-thio-D-ribo-hexopyranosyl trichloroacetimidate 
• 219702-30-4 Methyl 3-O,4-S-dibenzoyl-2,6-dideoxy-4-thio-α-D-ribo-hexopyranoside 

Relevant articles and documents

Synthesis of novel analogues of the calicheamicin γ1 and esperamicin A1B oligosaccharides

The chemical synthesis of three analogues of the calicheamicin γ1 and esperamicin A1B 2 oligosaccharides is described in which the carbohydrate ring E is replaced by a basic side chain E'. Our synthetic strategy begins with ABE' fragment construction which possesses an unusual β N-O glycosidic bond. Glycosylation of the nitrone 20 and the appropriate activated sugar B 13 or 22 gives the disaccharides 23 and 24 respectively. Esperamicin A1B oligosaccharide analogue 5 is obtained after two deprotection steps of the fragment 24. After removal of the protecting groups of unit 23, the fully deprotected disulfide 33 is reduced and immediately coupled with the deprotected aromatic unit C 30 (or CD 31) to provide the calicheamicin γ1 oligosaccharide analogues 3 and 4. We also report the synthesis of hemiacetal 7 in which the thioester function between the CD and B rings is replaced by an ester linkage. This arylsaccharide is a key intermediate required for the synthesis of a novel calicheamicin γ1 analogue 6.