219834-80-7 Usage
Description
2-[4-(Boc-aMino)-3-pyridyl]ethanol is an organic compound characterized by its unique molecular structure, which features a Boc-protected amino group and a pyridyl moiety. 2-[4-(Boc-aMino)-3-pyridyl]ethanol is known for its potential applications in various fields due to its versatile chemical properties.
Uses
Used in Chemical Synthesis:
2-[4-(Boc-aMino)-3-pyridyl]ethanol is used as a reagent for the preparation of stable biaryl analogues. These analogues serve as novel chiral nucleophilic catalysts, which are essential in the field of asymmetric catalysis. The application reason is that the compound's structure allows for the creation of catalysts with enhanced selectivity and reactivity in various chemical reactions.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-[4-(Boc-aMino)-3-pyridyl]ethanol is used as a building block for the synthesis of various drug candidates. The application reason is its ability to provide a diverse range of molecular structures with potential therapeutic properties, making it a valuable tool in drug discovery and development.
Used in Material Science:
2-[4-(Boc-aMino)-3-pyridyl]ethanol can also be utilized in the development of new materials with specific properties, such as optical, electronic, or mechanical characteristics. The application reason is its potential to form novel molecular structures that can be tailored for specific applications in material science.
Check Digit Verification of cas no
The CAS Registry Mumber 219834-80-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,9,8,3 and 4 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 219834-80:
(8*2)+(7*1)+(6*9)+(5*8)+(4*3)+(3*4)+(2*8)+(1*0)=157
157 % 10 = 7
So 219834-80-7 is a valid CAS Registry Number.
219834-80-7Relevant articles and documents
USE OF FLUORINATED DERIVATIVES OF 4-AMINOPYRIDINE IN THERAPEUTICS AND MEDICAL IMAGING
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Paragraph 00199, (2013/12/03)
The present disclosure provides novel compounds, including compounds that bind to potassium channels, methods for their manufacture, and methods for their use, including for the treatment of demyelinating diseases and/or in vivo imaging of the central nervous system to diagnose and/or assess the progression of MS or other diseases.
Configurationally Stable Biaryl Analogues of 4-(Dimethylamino)pyridine: A Novel Class of Chiral Nucleophilic Catalysts
Spivey, Alan C.,Fekner, Tomasz,Spey, Sharon E.,Adams, Harry
, p. 9430 - 9443 (2007/10/03)
A short synthetic approach toward a novel class of chiral nucleophilic catalysts, the dissymmetry of which stems from restricted rotation about an Ar-Ar bond, has been developed. The key steps of the synthesis include preparation of a nucleophilic 1-methyl-2-pyrrolino[3,2-c]pyridine core 16 by ortho-lithiation and creation of the biaryl axes via Suzuki cross-coupling reactions. Comparative HPLC studies of racemization for configurationally labile biaryls 31, 38, and 43 containing 1-methyl-2-pyrrolino[3,2-c]pyridine, 4-(dimethylamino)pyridine, and 4-(1-pyrrolidino)pyridine cores, respectively, have demonstrated that a pyrrolidino substituent ortho to the biaryl axis is optimal for slowing Ar-Ar rotation. Biaryls containing all three cores have been shown to retain DMAP-like catalytic activity in the acylation of a hindered alcohol. Biaryls 55 and 56, which are configurationally stable at ambient temperature, have also been prepared via modification of configurationally labile derivatives. Compounds 55 and 56 in optically pure form should provide a useful starting point for studies on catalytic asymmetric acyl transfer using atropisomeric analogues of DMAP.
