22002-87-5

Basic information

• Product Name: 2-hydroxy-3-(phosphonooxy)propyl oleate
• Synonyms: 2-hydroxy-3-(phosphonooxy)propyl oleate;(2-hydroxy-3-phosphonooxypropyl) (E)-octadec-9-enoate;1-Oleoyl-lysophosphatidic acid;monooleylphosphatidic acid;(Z)-9-Octadecenoic acid 2-hydroxy-3-(phosphonooxy)propyl ester;1-Oleoyl-2-lysophosphatidic acid;1-O-Oleoylglycerol 3-phosphoric acid;1-O-Oleoyl-sn-glycerol 3-phosphoric acid
• CAS NO: 22002-87-5
• Molecular Formula: C₂₁H₄₁O₇P
• Molecular Weight: 436.519801
• EINECS: 244-710-0
• Mol File: 22002-87-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 581.5°Cat760mmHg
• Flash Point: 305.5°C
• Appearance: /
• Density: 1.103g/cm³
• Vapor Pressure: 6.04E-16mmHg at 25°C
• Refractive Index: 1.489
• CAS DataBase Reference: 2-hydroxy-3-(phosphonooxy)propyl oleate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-hydroxy-3-(phosphonooxy)propyl oleate(22002-87-5)
• EPA Substance Registry System: 2-hydroxy-3-(phosphonooxy)propyl oleate(22002-87-5)

Safety Data

• Hazardous Substances Data: 22002-87-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C21H41O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(23)27-18-20(22)19-28-29(24,25)26/h9-10,20,22H,2-8,11-19H2,1H3,(H2,24,25,26)/b10-9+

Upstream product

• 68737-67-7 dioleoylphosphatidylcholine 

Relevant articles and documents

Biosynthesis of castor oil: Effect of polyamines on the acylation of lysophosphatidic acid at the sn-2 position with ricinoleic acid

Polyamines with diamine structures of chain length longer than 3C were essential for the synthesis of phosphatidic acid (PA) from ricinoleoyl-CoA and lysophosphatidic acid (LPA) by the castor LPA acyltransferase reaction, suggesting that polyamines modulate enzyme affinity for the acyl-CoA substrate in vivo.

Methods of using lysophosphatidic acids for regulating skin wrinkles

The subject invention relates to methods for regulating wrinkles in mammalian skin comprising topical application of a lysophosphatidic acid compound having the structure: STR1 or a cyclic derivative thereof having the structure: STR2 or a pharmaceutically acceptable salt thereof, wherein --R is unsubstituted or substituted, saturated or unsaturated, straight or branched chain alkyl having from 12 to about 23 carbon atoms; each --X-- is independently --O-- or --S--; and --Y-- is --O-- or --CH2 --.