220029-96-9 Usage
General Description
(S)-APIC, or (S)-2-amino-3-(3-hydroxy-5-pentylphenyl)propanoic acid, is a chemical compound that is found in certain strains of the bacteria Pseudomonas fluorescens. It has been identified as a key molecule in the ability of these bacteria to suppress the growth of certain plant pathogens, making it a potential candidate for use in biological control of crop diseases. (S)-APIC has been shown to have antimicrobial activity against a variety of pathogenic fungi, and it is thought to function by interfering with the growth and development of these organisms. Further research is still needed to fully understand the mechanism of action of (S)-APIC and its potential applications in agriculture and medicine.
Check Digit Verification of cas no
The CAS Registry Mumber 220029-96-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,0,0,2 and 9 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 220029-96:
(8*2)+(7*2)+(6*0)+(5*0)+(4*2)+(3*9)+(2*9)+(1*6)=89
89 % 10 = 9
So 220029-96-9 is a valid CAS Registry Number.
220029-96-9Relevant articles and documents
Organocatalytic enantioselective synthesis of metabotropic glutamate receptor ligands
Suri, Jeff T.,Steiner, Derek D.,Barbas III, Carlos F.
, p. 3885 - 3888 (2007/10/03)
(Chemical Equation Presented) (R)-Proline catalyzes the amination reaction of functionalized indane carboxaldehydes and allows for the efficient enantioselective synthesis (>99% ee) of the metabotropic glutamate receptor ligands (S)-AIDA and (S)-APICA.
Synthesis and biological activity of cyclic analogues of MPPG and MCPG as metabotropic glutamate receptor antagonists
Ma, Dawei,Tian, Hongqi,Sun, Hongbin,Kozikowski, Alan P.,Pshenichkin, Sergey,Wroblewski, Jarda T.
, p. 1195 - 1198 (2007/10/03)
The synthesis of two rigidified phenylglycine analogues is disclosed. The cyclic analogue 1 of (R,S)-α-methyl-4-phosphonophenylglycine (MPPG) is shown to be a particularly interesting pharmacological tool, for it is a group II selective mGluR antagonist that possesses an inverse agonist-like action.
