220155-44-2

Basic information

• Product Name: 2-fluoro-2-(phenylsulfanyl)acetamide
• Synonyms: 2-fluoro-2-(phenylsulfanyl)acetamide
• CAS NO: 220155-44-2
• Molecular Weight: 185.222
• Mol File: 220155-44-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-fluoro-2-(phenylsulfanyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-fluoro-2-(phenylsulfanyl)acetamide(220155-44-2)
• EPA Substance Registry System: 2-fluoro-2-(phenylsulfanyl)acetamide(220155-44-2)

Safety Data

• Hazardous Substances Data: 220155-44-2(Hazardous Substances Data)

Upstream product

• 22446-20-4 α-(phenylthio)acetamide 
• 106372-59-2 ethyl 2-fluoro-2-(phenylsulfanyl)acetate 
• 108-98-5 thiophenol 

Downstream Products

• 92963-26-3 3-benzoyl-2-(phenylsulfanyl)propionamide 

Relevant articles and documents

Effect of solvents on the selective electrofluorination of aromatic compounds containing active methylene groups

Voltammetry and constant current electrolysis was used to study the oxidative fluorination of PhSCH2COOMe, PhSCH2CONH2, PhSCH2COOPh and PhCH2CN in solvent-free and Et3N*3HF and Et3N*3HF dissolved in CH3CN, THF, DME and sulfolane. Sulfolane, DME and THF containig Et3N*3HF show much lower oxidation limits when compared to CH3CN/Et3N*3HF. These compounds udergo simultaneous oxidation along with background oxidation processes. Solvent-free Et3N*3HF has a much wider anodic potential range for the oxidation of organic compounds. Selective electrofluorination of PhSCH2COOPh does not show significant solvent effects. THF and DME were found to be more efficient for the selective fluorination of PhSCH2CONH2 and PhCH2CN compared to CH3CN. - Keywords: Selective electrofluorination; Active methylene compounds; Solvent effects

Adsorption effects on the selective electrofluorination of α-(phenylthio)acetamides and α-(phenylthio)acetates in Et3N·3HF/CH3CN

Cyclic voltammetric behaviour of α-(phenylthio)acetamides and α-(phenylthio)acetates were compared in CH3CN/tetrabutylammonium perchlorate (TBAP) and CH3CN/Et3N·3HF to assess the influence of fluoride ion on the oxidative