220180-55-2

Basic information

• Product Name: 4-FLUORO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID METHYL ESTER
• Synonyms: 4-FLUORO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID METHYL ESTER;Methyl 4-fluoro-1-benzothiophene-2-carboxylate, 4-Fluoro-2-(methoxycarbonyl)-1-benzothiophene;4-Fluoro-benzo[b]thiophene-2-carboxylic acid ethyl ester;METHYL 4-FLUORO-2,3-DIHYDROBENZO[B]THIOPHENE-2-CARBOXYLATE
• CAS NO: 220180-55-2
• Molecular Formula: C10H7FO2S
• Molecular Weight: 210.23
• Mol File: 220180-55-2.mol
• Article Data: 9

Chemical Properties

• Melting Point: 96-98°
• Boiling Point: 308.3°C at 760 mmHg
• Flash Point: 140.3°C
• Appearance: /
• Density: 1.355g/cm³
• Vapor Pressure: 0.000685mmHg at 25°C
• Refractive Index: 1.616
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 4-FLUORO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 4-FLUORO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID METHYL ESTER(220180-55-2)
• EPA Substance Registry System: 4-FLUORO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID METHYL ESTER(220180-55-2)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 220180-55-2(Hazardous Substances Data)

Usage

General Description

4-Fluoro-Benzo[b]thiophene-2-carboxylic Acid Methyl Ester is a chemical compound with a molecular formula of C10H7FO2S. 4-FLUORO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID METHYL ESTER falls into the category of aromatic esters, specifically, a benzo[b]thiophene, which is a polycyclic aromatic hydrocarbon (PAH) that contains a benzene fused to thiophene. The presence of the fluorine atom shows that the compound is also a halogenated benzo[b]thiophene. This chemical compound is generally used in scientific research and as an intermediate in organic synthesis. However, details regarding its physical properties such as melting point, boiling point, and specific rotation are limited, which suggests the compound is largely used in specific and controlled laboratory conditions.

InChI:InChI=1/C10H7FO2S/c1-13-10(12)9-5-6-7(11)3-2-4-8(6)14-9/h2-5H,1H3

Upstream product

• 437-81-0 2,6-difluorobenzaldehyde 
• 2365-48-2 Methyl thioglycolate 
• 67-56-1 methanol 
• 372-18-9 1,3-Difluorobenzene 
• 310466-37-6 4-fluoro-1-benzothiophene-2-carboxylic acid 

Downstream Products

• 957059-61-9 (4-fluoro-benzo[b]thiophen-2-yl)-methanol 
• 310466-37-6 4-fluoro-1-benzothiophene-2-carboxylic acid 
• 310466-38-7 4-fluorobenzo[b]thiophene 

Relevant articles and documents

Enantioselective Synthesis of Five-Membered-Ring Atropisomers with a Chiral Rh(III) Complex

Axially chiral atropisomeric compounds are widely applied in asymmetric catalysis and medicinal chemistry, and efficient methods for their synthesis are in high demand. This applies in particular to atropisomers derived from five-membered aromatic rings because their lower barrier for rotation among the biaryl axis limits their asymmetric synthesis. We report here an enantioselective C-H functionalization method using our chiral RhJasCp complex for the synthesis of the biaryl atropisomer types that can be accessed from three different five-membered-ring heterocycles.

Design and development of cyclometalated ruthenium complexes containing thiophenyl-pyridine ligand for dye-sensitized solar cells

Two new cyclometalated ruthenium sensitizers NC102 (1) and NC103 (2), where the two NCS- ligands of the N3 analog were replaced with the 2-thiophen-2-yl-pyridine and 2-benzo[b]thiophen-2-yl-pyridine ligands, respectively, were designed and synthesized for dye-sensitized solar cell applications. The effects of these two ligands on the photophysical behavior of ruthenium complexes were investigated by their optical, electrochemical, and photovoltaic properties. The sensitizer NC103 (2) with the fluoride substitution in the ligand exhibited the best cell performance with a short-circuit current (Jsc) of 9.45 mA/cm2, an open-circuit voltage (V oc) of 630 mV, and a fill factor (FF) of 0.71, giving an overall power conversion efficiency of (η) 4.22% under simulated AM 1.5 irradiation.

COLD MENTHOL RECEPTOR-1 ANTAGONISTS

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