2202-17-7 Usage
Description
O-METHYLDAURICINE, also known as (-)-O-Methyldauricine, is an isoquinoline derivative that can be extracted from various plant sources. It is a bioactive compound with demonstrated antibacterial properties and the ability to modulate chloroquine resistance in Plasmodium falciparum, which is the parasite responsible for causing malaria.
Uses
Used in Pharmaceutical Applications:
O-METHYLDAURICINE is used as an antibacterial agent for its ability to combat bacterial infections. Its effectiveness against certain bacteria makes it a potential candidate for the development of new antibiotics, especially in the context of increasing antibiotic resistance.
Additionally, O-METHYLDAURICINE is used as an antimalarial agent for its role in modulating chloroquine resistance in Plasmodium falciparum. This application is significant as it addresses the challenge of drug-resistant malaria, which is a major global health concern.
Check Digit Verification of cas no
The CAS Registry Mumber 2202-17-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,2,0 and 2 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 2202-17:
(6*2)+(5*2)+(4*0)+(3*2)+(2*1)+(1*7)=37
37 % 10 = 7
So 2202-17-7 is a valid CAS Registry Number.
InChI:InChI=1/C39H46N2O6/c1-40-16-14-27-21-35(43-4)37(45-6)23-30(27)32(40)18-25-8-11-29(12-9-25)47-39-20-26(10-13-34(39)42-3)19-33-31-24-38(46-7)36(44-5)22-28(31)15-17-41(33)2/h8-13,20-24,32-33H,14-19H2,1-7H3/t32-,33-/m1/s1
2202-17-7Relevant articles and documents
DAURICINE PRODUCTION IN CULTURED ROOTS OF MENISPERMUM DAURICUM
Sugimoto, Yukihiro,Yoshida, Akihiko,Uchida, Shinji,Inanaga, Shinobu,Yamada, Yasuyuki
, p. 679 - 684 (1994)
Root cultures of Menispermum dauricum were established from adventitious roots formed on the leaf segments.These roots produce dauricine as a major constituent and the optimum conditions for dauricine production in cultured roots were investigated. a dauricine content of more than 0.5percent dry weight was achieved in Gamborg's B5 medium containing 3percent surcose and 7.5 μM NAA.Tyrosine and tyramine, possible precursors of dauricinine, increased dauricine formation.There was a positive correlation between dauricine content and root growth.