220227-84-9 Usage
General Description
3-(Trifluoromethoxy)benzenesulfonyl chloride is a chemical compound with the molecular formula C7H4ClF3O3S. It is a sulfonyl chloride derivative of trifluoromethylphenol and is used as a reagent in organic synthesis. 3-(Trifluoromethoxy)benzenesulfonyl chloride is a strong electrophile and is commonly used in the production of pharmaceuticals and agrochemicals, as well as in the synthesis of other organic compounds. It is also a key intermediate in the preparation of various functionalized sulfonyl compounds, and its reactivity makes it a valuable tool in chemical transformations. Additionally, 3-(Trifluoromethoxy)benzenesulfonyl chloride is known for its ability to introduce the trifluoromethoxy functional group into various organic molecules, making it a versatile and important building block in the field of organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 220227-84-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,0,2,2 and 7 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 220227-84:
(8*2)+(7*2)+(6*0)+(5*2)+(4*2)+(3*7)+(2*8)+(1*4)=89
89 % 10 = 9
So 220227-84-9 is a valid CAS Registry Number.
InChI:InChI=1/C7H4ClF3O3S/c8-15(12,13)6-3-1-2-5(4-6)14-7(9,10)11/h1-4H
220227-84-9Relevant articles and documents
Synthesis of aryl sulfonamides via palladium-catalyzed chlorosulfonylation of arylboronic acids
Debergh, J. Robb,Niljianskul, Nootaree,Buchwald, Stephen L.
supporting information, p. 10638 - 10641 (2013/08/23)
A palladium-catalyzed method for the preparation of sulfonamides is described. The process exhibits significant functional group tolerance and allows for the preparation of a number of arylsulfonyl chlorides and sulfonamides under mild conditions.
