220263-59-2

Basic information

• Product Name: (R_S)-2-methyl-N-(1-phenylethylidene)propane-2-sulfinamide
• Synonyms: (R_S)-2-methyl-N-(1-phenylethylidene)propane-2-sulfinamide
• CAS NO: 220263-59-2
• Molecular Weight: 223.339
• Mol File: 220263-59-2.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: (R_S)-2-methyl-N-(1-phenylethylidene)propane-2-sulfinamide(CAS DataBase Reference)
• NIST Chemistry Reference: (R_S)-2-methyl-N-(1-phenylethylidene)propane-2-sulfinamide(220263-59-2)
• EPA Substance Registry System: (R_S)-2-methyl-N-(1-phenylethylidene)propane-2-sulfinamide(220263-59-2)

Safety Data

• Hazardous Substances Data: 220263-59-2(Hazardous Substances Data)

Upstream product

• 917-54-4 methyllithium 
• 100-47-0 benzonitrile 
• 67734-35-4 (R)-tert-butyl tert-butanethiosulfinate 
• 98-86-2 acetophenone 
• 196929-78-9 (R)-2-methylpropane-2-sulfinamide 

Downstream Products

• 909296-45-3 (R_S,S)-N-[3-(N-tosylamino)-1-phenyl-3-(p-methyl-phenyl)-propylidene]-tert-butanesulfinamide 
• 131154-18-2 (-)-(S)-1-methyl-1-phenyl-3-butenamine 
• 247236-71-1 (R_S)-2-methyl-N-((R)-1-phenylethyl)propane-2-sulfinamide 
• 196929-95-0 (R_S)-2-methyl-N-((S)-1-phenylethyl)propane-2-sulfinamide 
• 909296-49-7 (R_S,S)-N-[3-(furan-2-yl)-3-(N-tosylamino)-1-phenyl-propylidene]-tert-butanesulfinamide 
• 909296-48-6 (R_S,S)-N-[3-(N-tosylamino)-3-(o-bromo-phenyl)-1-phenyl-propylidene]-tert-butanesulfinamide 
• 909296-47-5 (R_S,S)-N-[3-(N-tosylamino)-3-(o-methoxy-phenyl)-1-phenyl-propylidene]-tert-butanesulfinamide 
• 909296-50-0 (R_S,S)-N-[3-(N-tosylamino)-1-phenyl-3-(2-phenyl-vinyl)-propylidene]-tert-butanesulfinamide 
• 909296-43-1 (R_S,S)-N-[3-(N-tosylamino)-3-(p-chloro-phenyl)-1-phenyl-propylidene]-tert-butanesulfinamide 
• 909296-46-4 (R_S,S)-N-[3-(N-tosylamino)-1-phenyl-3-(p-methoxy-phenyl)-propylidene]-tert-butanesulfinamide 
• 909296-42-0 (R_S,S)-N-[3-(N-tosylamino)-1,3-diphenyl-propylidene]-tert-butanesulfinamide 

Relevant articles and documents

One-pot asymmetric synthesis of either diastereomer of tert-butanesulfinyl- protected amines from ketones

A one-pot method for the asymmetric synthesis of tert-butanesulfinyl- protected amines is described. Condensation of aryl alkyl and dialkyl ketones with tert-butanesulfinamide followed by in situ reduction with the appropriate reagent provides either dias

Highly efficient asymmetric construction of quaternary carbon-containing homoallylic and homopropargylic amines

A highly efficient method for the asymmetric synthesis of chiral quaternary carbon-containing homoallylic and homopropargylic amines under mild conditions was achieved with good yields and high diastereoselectivities.

Cycloaddition of chiral tert -butanesulfinimines with trimethylenemethane

The cycloaddition of chiral tert-butanesulfinimines with trimethylenemethane is found to give facile access to methylene-pyrrolidines with good yields and diastereoselectivities. The full scope of the cycloaddition is explored, and a range of transformations of the formed methylenepyrrolidines to give a range of functionalized chiral pyrrolidines is presented.