220270-63-3

Basic information

• Product Name: Ethanone, 2-bromo-1-(1-methyl-1H-pyrrol-3-yl)- (9CI)
• Synonyms: Ethanone, 2-bromo-1-(1-methyl-1H-pyrrol-3-yl)- (9CI)
• CAS NO: 220270-63-3
• Molecular Formula: C7H8BrNO
• Molecular Weight: 202.04852
• Product Categories: ACETYLHALIDE
• Mol File: 220270-63-3.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Ethanone, 2-bromo-1-(1-methyl-1H-pyrrol-3-yl)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 2-bromo-1-(1-methyl-1H-pyrrol-3-yl)- (9CI)(220270-63-3)
• EPA Substance Registry System: Ethanone, 2-bromo-1-(1-methyl-1H-pyrrol-3-yl)- (9CI)(220270-63-3)

Safety Data

• Hazardous Substances Data: 220270-63-3(Hazardous Substances Data)

Upstream product

• 932-62-7 3-acetyl-1-methyl-1H-pyrrole 

Relevant articles and documents

Indole compounds as COX-2 inhibitors

This invention provides a compound of the following formula: and the pharmaceutically acceptable salts thereof, wherein L is oxygen or sulfur; Y is a direct bond or C1-4alkylidene; Q is C1-6alkyl, C3-7cycloalkyl, phenyl, naphthyl, heteroaryl or the like; R1is hydrogen, C1-6alkyl or the like; R2is hydrogen, C1-4alkyl, C(O)R5wherein R5is C1-22alkyl or C2-22alkenyl, halosubstituted C1-8alkyl, halosubstituted C2-8alkenyl, —Y—C3-7cycloalkyl, —Y—C3-7cycloalkenyl, phenyl, naphthyl, heteroaryl or the like; X is halo, C1-4alkyl, hydroxy, C1-4alkoxy or the like; and n is 0, 1, 2 or 3, with the proviso that a group of formula —Y—Q is not methyl or ethyl when X is hydrogen; L is oxygen; R1is hydrogen; and R2is acetyl. This invention also provides a pharmaceutical composition useful for the treatment of a medical condition in which prostaglandins are implicated as pathogens.