220364-45-4Relevant articles and documents
An Efficient Total Synthesis of (+/-)-Sinulariol-B
Yue, Xiangjun,Lan, Jiong,Li, Jing,Liu, Zuosheng,Lin, Yulin
, p. 133 - 140 (2007/10/03)
The first total synthesis of (+/-)-Sinulariol-B, a marine cembrandiol, was achieved in ten steps and ca. 10 percent overall yield from E-geraniol (8). The key steps were the coupling of sulfone 7 with allylic chloride 6 and the macrocyclization of precursor 5 by sulfone- and thioether-stabilized carbanionic alkylations, respectively.