220453-60-1

Basic information

• Product Name: 2-bromo-3-chlorobenzyl bromide
• Synonyms: 2-bromo-3-chlorobenzyl bromide
• CAS NO: 220453-60-1
• Molecular Weight: 284.378
• Mol File: 220453-60-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-bromo-3-chlorobenzyl bromide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-bromo-3-chlorobenzyl bromide(220453-60-1)
• EPA Substance Registry System: 2-bromo-3-chlorobenzyl bromide(220453-60-1)

Safety Data

• Hazardous Substances Data: 220453-60-1(Hazardous Substances Data)

Upstream product

• 69190-56-3 2-bromo-1-chloro-3-methylbenzene 
• 34241-39-9 azobisisobutyronitrile 

Downstream Products

• 1021089-12-2 2-bromo-3-chlorophenylacetic acid methyl ester 

Relevant articles and documents

DIBENZOHETEROCYCLIC COMPOUND AND PREPARATION METHOD AND APPLICATION THEREOF

A dibenzoheterocyclic compound wherein band gaps of HOMO and LUMO energy levels of the dibenzoheterocyclic compound are wide, light can be emitted in a deep blue light-emitting region; and the LUMO energy level of the dibenzoheterocyclic compound is low, so the LUMO energy level matches with an electron transport layer for electrons injection and transport. The dibenzoheterocyclic compound has hole transport performance, so as a light-emitting layer material, the dibenzoheterocyclic compound balances the ratio of electrons to holes in a light-emitting layer increasing the combination probability and improving the device light-emitting efficiency. The spatial configuration of the dibenzoheterocyclic compound avoids material stacking molecules, reduces annihilation of excitons, and inhibits efficiency roll-off. The dibenzoheterocyclic compound has thermal stability, so deep blue light can be emitted efficiently and stably. With an organic light-emitting diode and a deep blue light-emitting device with high light-emitting efficiency, low working voltage can be obtained.

HETEROARYL COMPOUNDS USEFUL AS INHIBITORS OF SUMO ACTIVATING ENZYME

Disclosed are chemical entities which are compounds of formula (I); or pharmaceutically acceptable salts thereof; wherein Y, Ra, Ra', Rb, Rc, X1, X2, X3, Rd, Z1, and Z2 have the values described herein and stereochemical configurations depicted at asterisked positions indicate absolute stereochemistry. Chemical entities according to the disclosure can be useful as inhibitors of Sumo Activating Enzyme (SAE). Further provided are pharmaceutical compositions comprising a compound of the disclosure and methods of using the compositions in the treatment of proliferative, inflammatory, cardiovascular, and neurodegenerative diseases or disorders.