220489-24-7

Basic information

• Product Name: 4-benzyloxy-3<(1S)-1,2,2-trimethylcyclopentyl>-2-cyclohexen-1-one
• Synonyms: 4-benzyloxy-3<(1S)-1,2,2-trimethylcyclopentyl>-2-cyclohexen-1-one
• CAS NO: 220489-24-7
• Molecular Weight: 312.452
• Mol File: 220489-24-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-benzyloxy-3<(1S)-1,2,2-trimethylcyclopentyl>-2-cyclohexen-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-benzyloxy-3<(1S)-1,2,2-trimethylcyclopentyl>-2-cyclohexen-1-one(220489-24-7)
• EPA Substance Registry System: 4-benzyloxy-3<(1S)-1,2,2-trimethylcyclopentyl>-2-cyclohexen-1-one(220489-24-7)

Safety Data

• Hazardous Substances Data: 220489-24-7(Hazardous Substances Data)

Upstream product

• 220489-22-5 2-benzyloxy-1-<(1S)-1,2,2-trimethylcyclopentyl>hexane-1,5-dione 
• 43209-86-5 3-trimethylsilyl-3-buten-2-one 
• 220489-20-3 2-benzyloxy-1-<(1S)-1,2,2-trimethylcyclopentyl>-1-ethanone 
• 100-39-0 benzyl bromide 
• 88794-46-1 (-)-2,2,6-trimethyl-7-oxabicyclo[4.1.0]heptane-1-methanol 
• 220489-17-8 (1aS,5aS)-1a-benzyloxymethyl-2,2,5a-trimethylperhydrobenzooxirene 

Downstream Products

• 220489-32-7 4-Benzyloxy-1-methyl-3-((S)-1,2,2-trimethyl-cyclopentyl)-cyclohex-2-enol 
• 220489-26-9 benzyl 4-methylene-2-<(1S)-1,2,2-trimethylcyclopentyl>-2-cyclohexenyl-ether 
• 286365-30-8 4-benzyloxy-6-bromo-3-[(1S)-1,2,2-trimethylcyclopentyl]-2-cyclohexen-1-one 
• 81784-10-3 4-methyl-2-[(1S)-1,2,2-trimethylcyclopentyl]phenol 
• 81784-18-1 1S-(5'-formyl-2'-hydroxyphenyl)-1,2,2-trimethylcyclopentane 
• 286365-37-5 (-)-4-hydroxymethyl-2-(1',2',2'-trimethylcyclopentyl)phenol 
• 286365-36-4 methyl 4-hydroxy-3-[(1S)-1,2,2-trimethylcyclopentyl]benzoate 
• 286365-34-2 1-benzyloxy-4-methyl-2-[(1S)-1,2,2-trimethylcyclopentyl]benzene 
• 286365-33-1 4-benzyloxy-3-[(1S)-1,2,2-trimethylcyclopentyl]benzaldehyde 
• 286365-31-9 4-benzyloxy-3-[(1S)-1,2,2-trimethylcyclopentyl]phenol 
• 286365-35-3 methyl 4-benzyloxy-3-[(1S)-1,2,2-trimethylcyclopentyl]benzoate 
• 286365-32-0 4-benzyloxy-3-[(1S)-1,2,2-trimethylcyclopentyl]phenyl trifluoromethanesulfonate 
• 80322-46-9 (-)-herbertene 
• 220489-28-1 4-Methyl-2-((S)-1,2,2-trimethyl-cyclopentyl)-cyclohex-2-enol 

Relevant articles and documents

Enantioselective synthesis of herbertane sesquiterpenes: Synthesis of (-)-α-formylherbertenol

The synthesis of 4-hydroxy-3-[(1S)-1,2,2-trimethylcyclopentyl]benzaldehyde [(-)-α-formylherbertenol 1], a herbertane-type sesquiterpene isolated from the leafy liverwort Herberta adunca, from β-cyclogeraniol is described. The synthesis is based on the previously described preparation of an enantiopure 1,2,2-trimethylcyclopentane synthon from which the characteristic aromatic moiety of 1 is elaborated, using a Robinson annulation and a palladium-catalysed methoxycarbonylation of an aryl triflate as key synthetic steps. The synthesis of the natural sesquiterpene (-)-α-herbertenol, also a natural sequiterpene, using the same methodology is also described. Copyright (C) 2000 Elsevier Science Ltd.