220565-63-9Relevant articles and documents
Fukuyama Cross-Coupling Approach to Isoprekinamycin: Discovery of the Highly Active and Bench-Stable Palladium Precatalyst POxAP
Tang, Shuang-Qi,Bricard, Jacques,Schmitt, Martine,Bihel, Frédéric
supporting information, p. 844 - 848 (2019/01/30)
An efficient and user-friendly palladium(II) precatalyst, POxAP (post-oxidative-addition precatalyst), was identified for use in Fukuyama cross-coupling reactions. Suitable for storage under air, the POxAP precatalyst allowed reaction between thioesters and organozinc reagents with turnover numbers of ～90000. A series of 23 ketones were obtained with yields ranging from 53 to 99%. As proof of efficacy, an alternative approach was developed for the synthesis of a key precursor of the natural product isoprekinamycin.
Cobalt-Catalyzed Formation of 2-Pyridylzinc Reagents and Their Subsequent Coupling
Linke, Stephanie,Manolikakès, Sofia M.,Auffrant, Audrey,Gosmini, Corinne
, p. 2595 - 2600 (2018/06/08)
The preparation of pyridylzinc compounds from the corresponding pyridyl halides using a cobalt catalyst is described. The complex employed features a polydentate N-heterocyclic ligand and allows the reaction to be carried out in the absence of pyridine as
A versatile organozinc approach to the synthesis of potential organic functional building blocks: 5-substituted 3-bromo-2-methylthiophene derivatives
Cheon, Jong-Woo,Cho, Hyun-Hee,Kim, Seung-Hoi
, p. 1266 - 1269 (2015/07/15)
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