220587-30-4

Basic information

• Product Name: N-acetyl-3-chloro-4-tetrahydropyranyloxy-aniline
• Synonyms: N-acetyl-3-chloro-4-tetrahydropyranyloxy-aniline
• CAS NO: 220587-30-4
• Molecular Weight: 269.728
• Mol File: 220587-30-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-acetyl-3-chloro-4-tetrahydropyranyloxy-aniline(CAS DataBase Reference)
• NIST Chemistry Reference: N-acetyl-3-chloro-4-tetrahydropyranyloxy-aniline(220587-30-4)
• EPA Substance Registry System: N-acetyl-3-chloro-4-tetrahydropyranyloxy-aniline(220587-30-4)

Safety Data

• Hazardous Substances Data: 220587-30-4(Hazardous Substances Data)

Upstream product

• 5345-54-0 3-chloro-4-methoxyaniline 
• 110-87-2 3,4-dihydro-2H-pyran 
• 3964-54-3 3-chloro-4-hydroxyacetanilide 
• 7073-42-9 N-(3-chloro-4-methoxyphenyl)acetamide 

Downstream Products

• 174668-87-2 3-chloro-4-tetrahydropyranyloxy-aniline 

Relevant articles and documents

Novel thiopyrano[3,2-b] and cycloalkeno[1,2-b]indole derivatives with high inhibitory properties in LTB4 production

Series of thiopyrano[3,2-b] and cycloalkeno[1,2-b]indoles were synthesized and evaluated in order to determine the necessary structural requirements for high leukotrienes biosynthesis inhibition. In vitro experiments showed that compounds 11b and 12b belonging to the second series were the most active and selective compounds on LTB4 production. Further in vivo investigations have shown additional very significant activity in the acute phorbol ester induced mouse ear swelling which is predictive of potential antipsoriatic properties.