220641-69-0Relevant articles and documents
METHOD FOR THE SYNTHESIS OF BENZAZOLE
-
Paragraph 0045, (2017/09/19)
PROBLEM TO BE SOLVED: To obtain a benzazole in a short reaction time with high yields. SOLUTION: A method for the synthesis of a benzazole includes a chemical reaction represented by the chemical reaction formula (1) to occur in subcritical water or supercritical water (X is NR6, O, or S. Y is H, OR7, halogen, or NR8R9. R1 to R9 are a C1-C20 aliphatic or aromatic substituent which may have O, N, S, B, Si, halogen, or P (two or more substituents of R1 to R6 may be coupled together, R8 and R9 may be coupled together, and two or more substituents of R1 to R9 may be the same) or H). SELECTED DRAWING: None COPYRIGHT: (C)2017,JPOandINPIT
COMPOUNDS FOR TREATMENT OF TRYPANOSOMES AND NEUROLOGICAL PATHOGENS AND USES THEREOF
-
Paragraph 0190, (2017/09/24)
The present invention relates to novel compounds that cross the blood-brain barrier and are effective inhibitors of neurological pathogens such as trypanosomes. The invention further relates to the use of these compounds for treating disorders related to trypanosomes and neurological pathogens.