220741-57-1Relevant articles and documents
Structure-activity relationship at the proximal phenyl group in a series of non-peptidyl N-type calcium channel antagonists
Ryder, Todd R.,Hu, Lain-Yen,Rafferty, Michael F.,Lotarski, Susan M.,Rock, David M.,Stoehr, Sally J.,Taylor, Charles P.,Weber, Mark L.,Miljanich, George P.,Millerman, Elizabeth,Szoke, Balazs G.
, p. 2453 - 2458 (1999)
Selective N-Type Voltage Sensitive Calcium Channel (VSCC) antagonists have shown utility in several models of pain and ischemia. We report the structure-activity relationship at the proximal phenyl group in a series of non-peptidyl VSCC blockers.