22083-48-3

Basic information

• Product Name: 4,4-diphenylhexan-3-one
• Synonyms: 4,4-diphenylhexan-3-one
• CAS NO: 22083-48-3
• Molecular Weight: 252.356
• Mol File: 22083-48-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4,4-diphenylhexan-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4-diphenylhexan-3-one(22083-48-3)
• EPA Substance Registry System: 4,4-diphenylhexan-3-one(22083-48-3)

Safety Data

• Hazardous Substances Data: 22083-48-3(Hazardous Substances Data)

Upstream product

• 22083-47-2 2-ethyl-1,1-diphenylbutane-1,2-diol 
• 93-55-0 1-phenyl-propan-1-one 
• 4437-51-8 3,4-hexanedione 
• 71-43-2 benzene 

Relevant articles and documents

Pinacol reduction-cum-rearrangement. A re-examination of the reduction of aryl alkyl ketones by zinc-aluminum chloride

Reduction of alkyl phenyl ketones by zinc and aluminum chloride in acetonitrile results in pinacol condensation followed by rearrangement. The phenyl group migrates in every instance.

Acid-catalyzed Reactions of 1,2-Dicarbonylethanes with Benzene. Ethylene Dication Electrophiles.

1,2-dicarbonyl compounds reacted with benzene in the presence of a strong acid, trifluoromethanesulfonic acid, to give gem-diphenylated ketones in high yields.The reaction was accelerated when the acidity of the medium was increased, supporting involvement of O,O-diprotonated 1,2-dicarbonyl species (i.e., 1,2-dihydroxyethylene dications) as the active electrophiles.