220830-64-8Relevant articles and documents
Conjugates of a dinuclear zinc(II) complex and DNA oligomers as novel sequence-selective artificial ribonucleases
Matsuda, Shigeo,Ishikubo, Akira,Kuzuya, Akinori,Yashiro, Morio,Komiyama, Makoto
, p. 3284 - 3286 (2007/10/03)
Even in the presence of a large excess of Zn(II) ions, sequence- selective RNA hydrolysis is achieved by DNA conjugates involving a dinuclear Zn(II) complex (shown schematically). This is because the cooperation of two Zn(II) ions is essential for the RNA